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Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug resistant Mycobacterium tuberculosis.
Harrison GA, Cho K, Wang ER, Sarkar S, Almqvist F, Patti GJ, Stallings CL. Harrison GA, et al. Among authors: stallings cl. bioRxiv [Preprint]. 2023 Feb 7:2023.02.06.527416. doi: 10.1101/2023.02.06.527416. bioRxiv. 2023. Update in: mBio. 2024 Mar 13;15(3):e0296823. doi: 10.1128/mbio.02968-23 PMID: 36798348 Free PMC article. Updated. Preprint.
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.
Flentie K, Harrison GA, Tükenmez H, Livny J, Good JAD, Sarkar S, Zhu DX, Kinsella RL, Weiss LA, Solomon SD, Schene ME, Hansen MR, Cairns AG, Kulén M, Wixe T, Lindgren AEG, Chorell E, Bengtsson C, Krishnan KS, Hultgren SJ, Larsson C, Almqvist F, Stallings CL. Flentie K, et al. Among authors: stallings cl. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10510-10517. doi: 10.1073/pnas.1818009116. Epub 2019 May 6. Proc Natl Acad Sci U S A. 2019. PMID: 31061116 Free PMC article.
Perspectives and Advances in the Understanding of Tuberculosis.
Kinsella RL, Zhu DX, Harrison GA, Mayer Bridwell AE, Prusa J, Chavez SM, Stallings CL. Kinsella RL, et al. Among authors: stallings cl. Annu Rev Pathol. 2021 Jan 24;16:377-408. doi: 10.1146/annurev-pathol-042120-032916. Annu Rev Pathol. 2021. PMID: 33497258 Review.
Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant.
Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F. Sarkar S, et al. Among authors: stallings cl. J Med Chem. 2023 Aug 24;66(16):11056-11077. doi: 10.1021/acs.jmedchem.3c00358. Epub 2023 Jul 24. J Med Chem. 2023. PMID: 37485869 Free PMC article.
Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responses.
Naik SK, McNehlan ME, Mreyoud Y, Kinsella RL, Smirnov A, Chowdhury CS, McKee SR, Dubey N, Woodson R, Kreamalmeyer D, Stallings CL. Naik SK, et al. Among authors: stallings cl. bioRxiv [Preprint]. 2023 Oct 5:2023.10.03.560720. doi: 10.1101/2023.10.03.560720. bioRxiv. 2023. Update in: Mucosal Immunol. 2024 Oct;17(5):1114-1127. doi: 10.1016/j.mucimm.2024.07.002 PMID: 37873329 Free PMC article. Updated. Preprint.
74 results