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Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse.
Duvick L, Southern WM, Benzow K, Burch ZN, Handler HP, Mitchell JS, Kuivinen H, Gadiparthi UK, Yang P, Soles A, Scheeler C, Rainwater O, Serres S, Lind E, Nichols-Meade T, O'Callaghan B, Zoghbi HY, Cvetanovic M, Wheeler VC, Ervasti JM, Koob MD, Orr HT. Duvick L, et al. Among authors: ervasti jm. bioRxiv [Preprint]. 2023 Jun 30:2023.02.08.527710. doi: 10.1101/2023.02.08.527710. bioRxiv. 2023. PMID: 36798410 Free PMC article. Preprint.
Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease.
Duvick L, Southern WM, Benzow KA, Burch ZN, Handler HP, Mitchell JS, Kuivinen H, Gadiparthi U, Yang P, Soles A, Sheeler CA, Rainwater O, Serres S, Lind EB, Nichols-Meade T, You Y, O'Callaghan B, Zoghbi HY, Cvetanovic M, Wheeler VC, Ervasti JM, Koob MD, Orr HT. Duvick L, et al. Among authors: ervasti jm. JCI Insight. 2024 Mar 21;9(9):e176057. doi: 10.1172/jci.insight.176057. JCI Insight. 2024. PMID: 38512434 Free PMC article.
Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy.
Guhathakurta P, Carter AL, Thompson AR, Kurila D, LaFrence J, Zhang L, Trask JR, Vanderheyden B, Muretta JM, Ervasti JM, Thomas DD. Guhathakurta P, et al. Among authors: ervasti jm. J Biol Chem. 2022 Dec;298(12):102675. doi: 10.1016/j.jbc.2022.102675. Epub 2022 Nov 11. J Biol Chem. 2022. PMID: 36372234 Free PMC article.
Dystrophin missense mutations alter focal adhesion tension and mechanotransduction.
Ramirez MP, Anderson MJM, Kelly MD, Sundby LJ, Hagerty AR, Wenthe SJ, Odde DJ, Ervasti JM, Gordon WR. Ramirez MP, et al. Among authors: ervasti jm. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2205536119. doi: 10.1073/pnas.2205536119. Epub 2022 Jun 14. Proc Natl Acad Sci U S A. 2022. PMID: 35700360 Free PMC article.
123 results