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A novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models.
Kowash RR, Sabnani M, Gray LT, Deng Q, Girard L, Naito Y, Masuhiro K, Minna JD, Gerber DE, Koyama S, Liu ZL, Baruah H, Akbay EA. Kowash RR, et al. Among authors: gray lt. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605880. doi: 10.1101/2024.07.30.605880. bioRxiv. 2024. Update in: J Immunother Cancer. 2025 Jan 6;13(1):e009867. doi: 10.1136/jitc-2024-009867 PMID: 39211152 Free PMC article. Updated. Preprint.
Tumor Cell-Surface Binding of Immune Stimulating Polymeric Glyco-Adjuvant via Cysteine-Reactive Pyridyl Disulfide Promotes Antitumor Immunity.
Slezak AJ, Mansurov A, Raczy MM, Chang K, Alpar AT, Lauterbach AL, Wallace RP, Weathered RK, Medellin JEG, Battistella C, Gray LT, Marchell TM, Gomes S, Swartz MA, Hubbell JA. Slezak AJ, et al. Among authors: gray lt. ACS Cent Sci. 2022 Oct 26;8(10):1435-1446. doi: 10.1021/acscentsci.2c00704. Epub 2022 Oct 7. ACS Cent Sci. 2022. PMID: 36313164 Free PMC article.
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker.
Mansurov A, Hosseinchi P, Chang K, Lauterbach AL, Gray LT, Alpar AT, Budina E, Slezak AJ, Kang S, Cao S, Solanki A, Gomes S, Williford JM, Swartz MA, Mendoza JL, Ishihara J, Hubbell JA. Mansurov A, et al. Among authors: gray lt. Nat Biomed Eng. 2022 Jul;6(7):819-829. doi: 10.1038/s41551-022-00888-0. Epub 2022 May 9. Nat Biomed Eng. 2022. PMID: 35534574 Free PMC article.
Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant.
Gray LT, Raczy MM, Briquez PS, Marchell TM, Alpar AT, Wallace RP, Volpatti LR, Sasso MS, Cao S, Nguyen M, Mansurov A, Budina E, Watkins EA, Solanki A, Mitrousis N, Reda JW, Yu SS, Tremain AC, Wang R, Nicolaescu V, Furlong K, Dvorkin S, Manicassamy B, Randall G, Wilson DS, Kwissa M, Swartz MA, Hubbell JA. Gray LT, et al. Biomaterials. 2021 Nov;278:121159. doi: 10.1016/j.biomaterials.2021.121159. Epub 2021 Sep 30. Biomaterials. 2021. PMID: 34634664 Free PMC article.
28 results