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11β-HSD1 determines the extent of muscle atrophy in a model of acute exacerbation of COPD.
Webster JM, Waaijenberg K, van de Worp WRPH, Kelders MCJM, Lambrichts S, Martin C, Verhaegen F, Van der Heyden B, Smith C, Lavery GG, Schols AMWJ, Hardy RS, Langen RCJ. Webster JM, et al. Among authors: smith c. Am J Physiol Lung Cell Mol Physiol. 2023 Apr 1;324(4):L400-L412. doi: 10.1152/ajplung.00009.2022. Epub 2023 Feb 21. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36807882 Free PMC article.
Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren's syndrome.
Nayar S, Campos J, Smith CG, Iannizzotto V, Gardner DH, Colafrancesco S, Pipi E, Kollert F, Hunter KJ, Brewer C, Buckley CD, Bowman SJ, Priori R, Valesini G, Juarez M, Fahy WA, Fisher BA, Payne A, Allen RA, Barone F. Nayar S, et al. Among authors: smith cg. Ann Rheum Dis. 2019 Feb;78(2):249-260. doi: 10.1136/annrheumdis-2017-212619. Epub 2018 Nov 24. Ann Rheum Dis. 2019. PMID: 30472652 Free PMC article.
Molecular and spatial analysis of tertiary lymphoid structures in Sjogren's syndrome.
Nayar S, Turner JD, Asam S, Fennell E, Pugh M, Colafrancesco S, Berardicurti O, Smith CG, Flint J, Teodosio A, Iannizzotto V, Gardner DH, van Roon J, Korsunsky I, Howdle D; Roche Fibroblast Network Consortium; Frei AP, Lassen KG, Bowman SJ, Ng WF, Croft AP, Filer A, Fisher BA, Buckley CD, Barone F. Nayar S, et al. Nat Commun. 2025 Jan 2;16(1):5. doi: 10.1038/s41467-024-54686-0. Nat Commun. 2025. PMID: 39747819 Free PMC article.
Tertiary Lymphoid Structures: Autoimmunity Goes Local.
Pipi E, Nayar S, Gardner DH, Colafrancesco S, Smith C, Barone F. Pipi E, et al. Among authors: smith c. Front Immunol. 2018 Sep 12;9:1952. doi: 10.3389/fimmu.2018.01952. eCollection 2018. Front Immunol. 2018. PMID: 30258435 Free PMC article. Review.
CXCL13 as biomarker for histological involvement in Sjögren's syndrome.
Colafrancesco S, Priori R, Smith CG, Minniti A, Iannizzotto V, Pipi E, Lucchesi D, Pontarini E, Nayar S, Campos J, Arienzo F, Fusconi M, Cerbelli B, Giordano C, Valesini G, Bombardieri M, Fisher BA, Barone F. Colafrancesco S, et al. Among authors: smith cg. Rheumatology (Oxford). 2020 Jan 1;59(1):165-170. doi: 10.1093/rheumatology/kez255. Rheumatology (Oxford). 2020. PMID: 31274159
Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction.
Nayar S, Pontarini E, Campos J, Berardicurti O, Smith CG, Asam S, Gardner DH, Colafrancesco S, Lucchesi D, Coleby R, Chung MM, Iannizzotto V, Hunter K, Bowman SJ, Carlesso G, Herbst R, McGettrick HM, Browning J, Buckley CD, Fisher BA, Bombardieri M, Barone F. Nayar S, et al. Commun Biol. 2022 May 4;5(1):413. doi: 10.1038/s42003-022-03344-6. Commun Biol. 2022. PMID: 35508704 Free PMC article.
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology.
Nayar S, Campos J, Smith CG, Iannizzotto V, Gardner DH, Mourcin F, Roulois D, Turner J, Sylvestre M, Asam S, Glaysher B, Bowman SJ, Fearon DT, Filer A, Tarte K, Luther SA, Fisher BA, Buckley CD, Coles MC, Barone F. Nayar S, et al. Among authors: smith cg. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13490-13497. doi: 10.1073/pnas.1905301116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213547 Free PMC article.
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