E-cadherin loss drives diffuse-type gastric tumorigenesis via EZH2-mediated reprogramming.
Zou G, Huang Y, Zhang S, Ko KP, Kim B, Zhang J, Venkatesan V, Pizzi MP, Fan Y, Jun S, Niu N, Wang H, Song S, Ajani JA, Park JI.
Zou G, et al. Among authors: ko kp.
J Exp Med. 2024 Apr 1;221(4):e20230561. doi: 10.1084/jem.20230561. Epub 2024 Feb 27.
J Exp Med. 2024.
PMID: 38411616
Free PMC article.
Genetically engineered murine gastric organoids showed that Cdh1 knock-out (KO), KrasG12D, Trp53 KO (EKP) accelerates tumorigenesis with immune evasion compared with KrasG12D, Trp53 KO (KP). ...
Genetically engineered murine gastric organoids showed that Cdh1 knock-out (KO), KrasG12D, Trp53 KO (EKP) accelerates tumorige …