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Enhancing Efficacy of TCR-engineered CD4 + T Cells Via Coexpression of CD8α.
Anderson VE, Brilha SS, Weber AM, Pachnio A, Wiedermann GE, Dauleh S, Ahmed T, Pope GR, Quinn LL, Docta RY, Quattrini A, Masters S, Cartwright N, Viswanathan P, Melchiori L, Rice LV, Sevko A, Gueguen C, Saini M, Tavano B, Abbott RJM, Silk JD, Laugel B, Sanderson JP, Gerry AB. Anderson VE, et al. Among authors: rice lv. J Immunother. 2023 May 1;46(4):132-144. doi: 10.1097/CJI.0000000000000456. Epub 2023 Feb 27. J Immunother. 2023. PMID: 36826388 Free PMC article.
Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10.
Dimeloe S, Rice LV, Chen H, Cheadle C, Raynes J, Pfeffer P, Lavender P, Richards DF, Nyon MP, McDonnell JM, Kemper C, Gooptu B, Hawrylowicz CM. Dimeloe S, et al. Among authors: rice lv. J Steroid Biochem Mol Biol. 2019 May;189:1-9. doi: 10.1016/j.jsbmb.2019.01.014. Epub 2019 Jan 25. J Steroid Biochem Mol Biol. 2019. PMID: 30690074 Free PMC article.