Chen L - Search Results

1

Discovery of pterostilbene analogs as novel NLRP3 inflammasome inhibitors for potential treatment of DSS-induced colitis in mice.

Ruan B, Rong M, Ming Z, Wang K, Liu X, Deng L, Zhang X, Xu K, Shi C, Gao T, Liu X, Chen L. Ruan B, et al. Among authors: chen l. Bioorg Chem. 2023 Apr;133:106429. doi: 10.1016/j.bioorg.2023.106429. Epub 2023 Feb 18. Bioorg Chem. 2023. PMID: 36841048

2

Diarylpentadienone derivatives (curcumin analogues): Synthesis and anti-inflammatory activity.

Wang ZS, Chen LZ, Zhou HP, Liu XH, Chen FH. Wang ZS, et al. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1803-1807. doi: 10.1016/j.bmcl.2017.02.056. Epub 2017 Feb 24. Bioorg Med Chem Lett. 2017. PMID: 28284806

3

Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivatives.

Guo WY, Chen LZ, Shen BN, Liu XH, Tai GP, Li QS, Gao L, Ruan BF. Guo WY, et al. Among authors: chen lz. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1678-1689. doi: 10.1080/14756366.2019.1664499. J Enzyme Inhib Med Chem. 2019. PMID: 31530032 Free PMC article.

4

Synthesis and biological evaluation of myricetin-pentadienone hybrids as potential anti-inflammatory agents in vitro and in vivo.

Liu C, Han X, Yu PJ, Chen LZ, Xue W, Liu XH. Liu C, et al. Bioorg Chem. 2020 Mar;96:103597. doi: 10.1016/j.bioorg.2020.103597. Epub 2020 Jan 29. Bioorg Chem. 2020. PMID: 32028063

5

Discovery of Novel Pterostilbene-Based Derivatives as Potent and Orally Active NLRP3 Inflammasome Inhibitors with Inflammatory Activity for Colitis.

Chen LZ, Zhang XX, Liu MM, Wu J, Ma D, Diao LZ, Li Q, Huang YS, Zhang R, Ruan BF, Liu XH. Chen LZ, et al. J Med Chem. 2021 Sep 23;64(18):13633-13657. doi: 10.1021/acs.jmedchem.1c01007. Epub 2021 Sep 10. J Med Chem. 2021. PMID: 34506712

6

Discovery of 4-((E)-3,5-dimethoxy-2-((E)-2-nitrovinyl)styryl)aniline derivatives as potent and orally active NLRP3 inflammasome inhibitors for colitis.

Zhang XX, Diao LZ, Chen LZ, Ma D, Wang YM, Jiang H, Ruan BF, Liu XH. Zhang XX, et al. Eur J Med Chem. 2022 Jun 5;236:114357. doi: 10.1016/j.ejmech.2022.114357. Epub 2022 Apr 7. Eur J Med Chem. 2022. PMID: 35428012

7

Synthesis and Biological Evaluation of Novel Phthalide Analogs-1,2,4-Oxadiazole Hybrids as Potential Anti-Inflammatory Agents.

Ruan B, Tang X, Guo W, Hu Y, Chen L. Ruan B, et al. Among authors: chen l. Chem Biodivers. 2022 Aug;19(8):e202200039. doi: 10.1002/cbdv.202200039. Epub 2022 Jul 7. Chem Biodivers. 2022. PMID: 35794072

8

Design and synthesis of pterostilbene derivatives bearing triazole moiety that might treat DSS-induced colitis in mice through modulation of NF-κB/MAPK signaling pathways.

Chen L, Wang K, Wang L, Wang W, Wang L, Wang W, Li J, Liu X, Wang M, Ruan B. Chen L, et al. Eur J Med Chem. 2024 Jan 5;263:115949. doi: 10.1016/j.ejmech.2023.115949. Epub 2023 Nov 17. Eur J Med Chem. 2024. PMID: 37989058

9

Design, synthesis, in vitro and in vivo biological evaluation of pterostilbene derivatives for anti-inflammation therapy.

Chen L, Wang K, Liu X, Wang L, Zou H, Hu S, Zhou L, Li R, Cao S, Ruan B, Cui Q. Chen L, et al. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2315227. doi: 10.1080/14756366.2024.2315227. Epub 2024 Feb 29. J Enzyme Inhib Med Chem. 2024. PMID: 38421003 Free PMC article.

10

Synthesis and Anti-Inflammatory Bowel Disease Activity of Pterostilbene Derivatives.

Zhang X, Li B, Liu X, Chen L, Ruan B, Xia C. Zhang X, et al. Among authors: chen l. Chem Biodivers. 2024 Nov;21(11):e202401081. doi: 10.1002/cbdv.202401081. Epub 2024 Oct 8. Chem Biodivers. 2024. PMID: 39126188

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