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MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding.
Massó-Vallés D, Beaulieu ME, Jauset T, Giuntini F, Zacarías-Fluck MF, Foradada L, Martínez-Martín S, Serrano E, Martín-Fernández G, Casacuberta-Serra S, Castillo Cano V, Kaur J, López-Estévez S, Morcillo MÁ, Alzrigat M, Mahmoud L, Luque-García A, Escorihuela M, Guzman M, Arribas J, Serra V, Larsson LG, Whitfield JR, Soucek L. Massó-Vallés D, et al. Among authors: alzrigat m. Cancer Res Commun. 2022 Feb 21;2(2):110-130. doi: 10.1158/2767-9764.CRC-21-0103. eCollection 2022 Feb. Cancer Res Commun. 2022. PMID: 36860495 Free PMC article.
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
Agarwal P, Alzrigat M, Párraga AA, Enroth S, Singh U, Ungerstedt J, Österborg A, Brown PJ, Ma A, Jin J, Nilsson K, Öberg F, Kalushkova A, Jernberg-Wiklund H. Agarwal P, et al. Among authors: alzrigat m. Oncotarget. 2016 Feb 9;7(6):6809-23. doi: 10.18632/oncotarget.6843. Oncotarget. 2016. PMID: 26755663 Free PMC article.
MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner.
Castell A, Yan Q, Fawkner K, Bazzar W, Zhang F, Wickström M, Alzrigat M, Franco M, Krona C, Cameron DP, Dyberg C, Olsen TK, Verschut V, Schmidt L, Lim SY, Mahmoud L, Hydbring P, Lehmann S, Baranello L, Nelander S, Johnsen JI, Larsson LG. Castell A, et al. Among authors: alzrigat m. Cancer Res Commun. 2022 Mar 31;2(3):182-201. doi: 10.1158/2767-9764.CRC-21-0019. eCollection 2022 Mar. Cancer Res Commun. 2022. PMID: 36874405 Free PMC article.
EZH2 inhibition sensitizes retinoic acid-driven senescence in synovial sarcoma.
Mushtaq M, Liaño-Pons J, Wang J, Alzrigat M, Yuan Y, Ruiz-Pérez MV, Chen Y, Kashuba E, Haglund de Flon F, Brodin B, Arsenian-Henriksson M. Mushtaq M, et al. Among authors: alzrigat m. Cell Death Dis. 2024 Nov 16;15(11):836. doi: 10.1038/s41419-024-07176-6. Cell Death Dis. 2024. PMID: 39550391 Free PMC article.
16 results