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2,173 results

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LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity.
Zheng R, Dunlap M, Lyu J, Gonzalez-Figueroa C, Bobkov G, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Vuong A, Flynn RA, Chang HY, Xiao X, Cheng C. Zheng R, et al. Among authors: chang hy. bioRxiv [Preprint]. 2023 Feb 24:2023.02.23.529804. doi: 10.1101/2023.02.23.529804. bioRxiv. 2023. Update in: Mol Cell. 2024 Jun 6;84(11):2087-2103.e8. doi: 10.1016/j.molcel.2024.05.004 PMID: 36865202 Free PMC article. Updated. Preprint.
hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing.
Zheng R, Dunlap M, Bobkov GOM, Gonzalez-Figueroa C, Patel KJ, Lyu J, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Le Roux CA, Bartels MD, Vuong A, Flynn RA, Chang HY, Van Nostrand EL, Xiao X, Cheng C. Zheng R, et al. Among authors: chang hy. Mol Cell. 2024 Jun 6;84(11):2087-2103.e8. doi: 10.1016/j.molcel.2024.05.004. Epub 2024 May 29. Mol Cell. 2024. PMID: 38815579
Escape from X inactivation is directly modulated by levels of Xist non-coding RNA.
Hauth A, Panten J, Kneuss E, Picard C, Servant N, Rall I, Pérez-Rico YA, Clerquin L, Servaas N, Villacorta L, Jung F, Luong C, Chang HY, Zaugg JB, Stegle O, Odom DT, Loda A, Heard E. Hauth A, et al. Among authors: chang hy. bioRxiv [Preprint]. 2024 Mar 12:2024.02.22.581559. doi: 10.1101/2024.02.22.581559. bioRxiv. 2024. PMID: 38559194 Free PMC article. Preprint.
Enhancer activation from transposable elements in extrachromosomal DNA.
Kraft K, Murphy SE, Jones MG, Shi Q, Bhargava-Shah A, Luong C, Hung KL, He BJ, Li R, Park SK, Weiser NE, Luebeck J, Bafna V, Boeke JD, Mischel PS, Boettiger AN, Chang HY. Kraft K, et al. Among authors: chang hy. bioRxiv [Preprint]. 2024 Sep 8:2024.09.04.611262. doi: 10.1101/2024.09.04.611262. bioRxiv. 2024. PMID: 39282372 Free PMC article. Preprint.
Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis.
Jones MG, Sun D, Min KHJ, Colgan WN, Tian L, Weir JA, Chen VZ, Koblan LW, Yost KE, Mathey-Andrews N, Russell AJC, Stickels RR, Balderrama KS, Rideout WM 3rd, Chang HY, Jacks T, Chen F, Weissman JS, Yosef N, Yang D. Jones MG, et al. Among authors: chang hy. bioRxiv [Preprint]. 2024 Oct 24:2024.10.21.619529. doi: 10.1101/2024.10.21.619529. bioRxiv. 2024. PMID: 39484491 Free PMC article. Preprint.
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change.
Dehkordi SR, Wong IT, Ni J, Luebeck J, Zhu K, Prasad G, Krockenberger L, Xu G, Chowdhury B, Rajkumar U, Caplin A, Muliaditan D, Coruh C, Jin Q, Turner K, Teo SX, Pang AWC, Alexandrov LB, Chua CEL, Furnari FB, Paulson TG, Law JA, Chang HY, Yue F, DasGupta R, Zhao J, Mischel PS, Bafna V. Dehkordi SR, et al. Among authors: chang hy. bioRxiv [Preprint]. 2023 Dec 13:2023.12.12.571349. doi: 10.1101/2023.12.12.571349. bioRxiv. 2023. PMID: 38168210 Free PMC article. Preprint.
Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells.
Cepika AM, Amaya L, Waichler C, Narula M, Mantilla MM, Thomas BC, Chen PP, Freeborn RA, Pavel-Dinu M, Nideffer J, Porteus M, Bacchetta R, Müller F, Greenleaf WJ, Chang HY, Roncarolo MG. Cepika AM, et al. Among authors: chang hy. bioRxiv [Preprint]. 2024 Mar 12:2024.03.07.582969. doi: 10.1101/2024.03.07.582969. bioRxiv. 2024. PMID: 38559096 Free PMC article. Preprint.
2,173 results