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Page 1
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter JC, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. Wieder N, et al. Among authors: gabriel kr. Cell Metab. 2023 May 2;35(5):887-905.e11. doi: 10.1016/j.cmet.2023.03.018. Epub 2023 Apr 18. Cell Metab. 2023. PMID: 37075753 Free PMC article.
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter J, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. Wieder N, et al. Among authors: gabriel kr. bioRxiv [Preprint]. 2023 Feb 20:2023.02.19.529127. doi: 10.1101/2023.02.19.529127. bioRxiv. 2023. Update in: Cell Metab. 2023 May 2;35(5):887-905.e11. doi: 10.1016/j.cmet.2023.03.018 PMID: 36865221 Free PMC article. Updated. Preprint.
Epidermal 1-O-acylceramides appear with the establishment of the water permeability barrier in mice and are produced by maturating keratinocytes.
Rabionet M, Bernard P, Pichery M, Marsching C, Bayerle A, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Asadi A, Ebel P, Hoekstra M, Dumas S, Ntambi JM, Jacobsson A, Willecke K, Medin JA, Jonca N, Sandhoff R. Rabionet M, et al. Among authors: gabriel kr. Lipids. 2022 May;57(3):183-195. doi: 10.1002/lipd.12342. Epub 2022 Mar 23. Lipids. 2022. PMID: 35318678
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.
Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer N, Song J, Kuruvilla L, Chitraju C, Boland S, Jang DK, von Grotthuss M, Costanzo MC, Rydén M, Olzmann JA, Flannick J, Burtt NP, Farese RV Jr, Walther TC. Mejhert N, et al. Among authors: gabriel kr. Dev Cell. 2022 Feb 7;57(3):387-397.e4. doi: 10.1016/j.devcel.2022.01.003. Dev Cell. 2022. PMID: 35134345 Free PMC article.
Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner.
Bayerle A, Marsching C, Rabionet M, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Herzer S, Jennemann R, Levade T, Medin JA, Sandhoff R. Bayerle A, et al. Among authors: gabriel kr. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158741. doi: 10.1016/j.bbalip.2020.158741. Epub 2020 May 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32474112
Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice.
Gluchowski NL, Gabriel KR, Chitraju C, Bronson RT, Mejhert N, Boland S, Wang K, Lai ZW, Farese RV Jr, Walther TC. Gluchowski NL, et al. Among authors: gabriel kr. Hepatology. 2019 Dec;70(6):1972-1985. doi: 10.1002/hep.30765. Epub 2019 Jun 26. Hepatology. 2019. PMID: 31081165 Free PMC article.
45 results