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Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
Seedorf K, Weber C, Vinson C, Berger S, Vuillard LM, Kiss A, Creusot S, Broux O, Geant A, Ilic C, Lemaitre K, Richard J, Hammoutene A, Mahieux J, Martiny V, Durand D, Melchiore F, Nyerges M, Paradis V, Provost N, Duvivier V, Delerive P. Seedorf K, et al. Among authors: creusot s. JHEP Rep. 2022 Dec 16;5(4):100651. doi: 10.1016/j.jhepr.2022.100651. eCollection 2023 Apr. JHEP Rep. 2022. PMID: 36866391 Free PMC article.
Characterization and Pharmacological Validation of a Preclinical Model of NASH in Göttingen Minipigs.
Duvivier V, Creusot S, Broux O, Helbert A, Lesage L, Moreau K, Lesueur N, Gerard L, Lemaitre K, Provost N, Hubert EL, Baltauss T, Brzustowski A, De Preville N, Geronimi J, Adoux L, Letourneur F, Hammoutene A, Valla D, Paradis V, Delerive P. Duvivier V, et al. Among authors: creusot s. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):293-305. doi: 10.1016/j.jceh.2021.09.001. Epub 2021 Sep 8. J Clin Exp Hepatol. 2022. PMID: 35535064 Free PMC article.