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Page 1
Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
Seedorf K, Weber C, Vinson C, Berger S, Vuillard LM, Kiss A, Creusot S, Broux O, Geant A, Ilic C, Lemaitre K, Richard J, Hammoutene A, Mahieux J, Martiny V, Durand D, Melchiore F, Nyerges M, Paradis V, Provost N, Duvivier V, Delerive P. Seedorf K, et al. Among authors: geant a. JHEP Rep. 2022 Dec 16;5(4):100651. doi: 10.1016/j.jhepr.2022.100651. eCollection 2023 Apr. JHEP Rep. 2022. PMID: 36866391 Free PMC article.
Translationally controlled tumor protein is a target of tumor reversion.
Tuynder M, Fiucci G, Prieur S, Lespagnol A, Géant A, Beaucourt S, Duflaut D, Besse S, Susini L, Cavarelli J, Moras D, Amson R, Telerman A. Tuynder M, et al. Among authors: geant a. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15364-9. doi: 10.1073/pnas.0406776101. Epub 2004 Oct 15. Proc Natl Acad Sci U S A. 2004. PMID: 15489264 Free PMC article.
Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter.
Fiucci G, Beaucourt S, Duflaut D, Lespagnol A, Stumptner-Cuvelette P, Géant A, Buchwalter G, Tuynder M, Susini L, Lassalle JM, Wasylyk C, Wasylyk B, Oren M, Amson R, Telerman A. Fiucci G, et al. Among authors: geant a. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3510-5. doi: 10.1073/pnas.0400177101. Epub 2004 Feb 25. Proc Natl Acad Sci U S A. 2004. PMID: 14985507 Free PMC article.
Anti-diabetic activity of fused PPARγ-SIRT1 ligands with limited body-weight gain by mimicking calorie restriction and decreasing SGK1 expression.
Pirat C, Dacquet C, Leclerc V, Hennuyer N, Beucher-Gaudin M, Zanirato G, Géant A, Staels B, Ktorza A, Farce A, Caignard DH, Berthelot P, Lebegue N. Pirat C, et al. Among authors: geant a. Eur J Med Chem. 2017 Sep 8;137:310-326. doi: 10.1016/j.ejmech.2017.06.006. Epub 2017 Jun 12. Eur J Med Chem. 2017. PMID: 28609708
Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants.
Rueda P, Harley E, Lu Y, Stewart GD, Fabb S, Diepenhorst N, Cremers B, Rouillon MH, Wehrle I, Geant A, Lamarche G, Leach K, Charman WN, Christopoulos A, Summers RJ, Sexton PM, Langmead CJ. Rueda P, et al. Among authors: geant a. PLoS One. 2016 Jan 19;11(1):e0146846. doi: 10.1371/journal.pone.0146846. eCollection 2016. PLoS One. 2016. PMID: 26785252 Free PMC article.
Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker.
Karaca M, Castel J, Tourrel-Cuzin C, Brun M, Géant A, Dubois M, Catesson S, Rodriguez M, Luquet S, Cattan P, Lockhart B, Lang J, Ktorza A, Magnan C, Kargar C. Karaca M, et al. Among authors: geant a. PLoS One. 2009;4(5):e5555. doi: 10.1371/journal.pone.0005555. Epub 2009 May 18. PLoS One. 2009. PMID: 19440374 Free PMC article.