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Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
Seedorf K, Weber C, Vinson C, Berger S, Vuillard LM, Kiss A, Creusot S, Broux O, Geant A, Ilic C, Lemaitre K, Richard J, Hammoutene A, Mahieux J, Martiny V, Durand D, Melchiore F, Nyerges M, Paradis V, Provost N, Duvivier V, Delerive P. Seedorf K, et al. JHEP Rep. 2022 Dec 16;5(4):100651. doi: 10.1016/j.jhepr.2022.100651. eCollection 2023 Apr. JHEP Rep. 2022. PMID: 36866391 Free PMC article.
Covalent Inhibitors of KEAP1 with Exquisite Selectivity.
Fejes I, Markacz P, Tatai J, Rudas M, Dunkel P, Gyuris M, Nyerges M, Provost N, Duvivier V, Delerive P, Martiny V, Bristiel A, Vidal B, Richardson W, Rothweiler EM, Tranberg-Jensen J, Manning CE, Sweeney MN, Chalk R, Huber KVM, Bullock AN, Herner A, Seedorf K, Vinson C, Weber C, Kotschy A. Fejes I, et al. Among authors: seedorf k. J Med Chem. 2024 Dec 12;67(23):21208-21222. doi: 10.1021/acs.jmedchem.4c02019. Epub 2024 Nov 21. J Med Chem. 2024. PMID: 39572012 Free PMC article.
Acute-phase serum amyloid A as a marker of insulin resistance in mice.
Scheja L, Heese B, Zitzer H, Michael MD, Siesky AM, Pospisil H, Beisiegel U, Seedorf K. Scheja L, et al. Among authors: seedorf k. Exp Diabetes Res. 2008;2008:230837. doi: 10.1155/2008/230837. Exp Diabetes Res. 2008. PMID: 18584041 Free PMC article.
29 results