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Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease.
Davidsson P, Eketjäll S, Eriksson N, Walentinsson A, Becker RC, Cavallin A, Bogstedt A, Collén A, Held C, James S, Siegbahn A, Stewart R, Storey RF, White H, Wallentin L. Davidsson P, et al. Among authors: eketjall s. Cardiovasc Res. 2023 Jul 4;119(7):1596-1605. doi: 10.1093/cvr/cvad039. Cardiovasc Res. 2023. PMID: 36869765
Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS.
Georgievska B, Gustavsson S, Lundkvist J, Neelissen J, Eketjäll S, Ramberg V, Bueters T, Agerman K, Juréus A, Svensson S, Berg S, Fälting J, Lendahl U. Georgievska B, et al. Among authors: eketjall s. J Neurochem. 2015 Feb;132(4):477-86. doi: 10.1111/jnc.12937. Epub 2014 Sep 18. J Neurochem. 2015. PMID: 25156639 Free article.
Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.
Swahn BM, Kolmodin K, Karlström S, von Berg S, Söderman P, Holenz J, Berg S, Lindström J, Sundström M, Turek D, Kihlström J, Slivo C, Andersson L, Pyring D, Rotticci D, Ohberg L, Kers A, Bogar K, von Kieseritzky F, Bergh M, Olsson LL, Janson J, Eketjäll S, Georgievska B, Jeppsson F, Fälting J. Swahn BM, et al. Among authors: eketjall s. J Med Chem. 2012 Nov 8;55(21):9346-61. doi: 10.1021/jm3009025. Epub 2012 Sep 17. J Med Chem. 2012. PMID: 22924815
Development of a highly sensitive liquid chromatography-mass spectrometry method to quantify plasma leukotriene E4 and demonstrate pharmacological suppression of endogenous 5-LO pathway activity in man.
Löfgren L, Forsberg GB, Davidsson P, Eketjäll S, Whatling C. Löfgren L, et al. Among authors: eketjall s. Prostaglandins Other Lipid Mediat. 2020 Oct;150:106463. doi: 10.1016/j.prostaglandins.2020.106463. Epub 2020 May 23. Prostaglandins Other Lipid Mediat. 2020. PMID: 32450304
MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.
Lloyd C, Freskgård PO, Newton P, Lowne D, Nickson A, Bogstedt A, Eketjäll S, Höglund K, Gustavsson S, Welsh F, Chessell T, McFarlane M, Bhat RV, Turner R, Perkinton MS, Santisteban Valencia Z, Lindqvist E, Pomfret M, Dudley AD, Vaughan TJ, Groves MT, Natanegara F, Feng Y, Sims JR, Proctor NK, Dage JL, Shering C, Tan K, Ostenfeld T, Billinton A, Chessell IP. Lloyd C, et al. Among authors: eketjall s. Alzheimers Dement. 2024 Nov;20(11):7762-7776. doi: 10.1002/alz.14238. Epub 2024 Sep 25. Alzheimers Dement. 2024. PMID: 39319998 Free PMC article.
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.
Leonard D, Svenungsson E, Dahlqvist J, Alexsson A, Ärlestig L, Taylor KE, Sandling JK, Bengtsson C, Frodlund M, Jönsen A, Eketjäll S, Jensen-Urstad K, Gunnarsson I, Sjöwall C, Bengtsson AA, Eloranta ML, Syvänen AC, Rantapää-Dahlqvist S, Criswell LA, Rönnblom L. Leonard D, et al. Among authors: eketjall s. Ann Rheum Dis. 2018 Jul;77(7):1063-1069. doi: 10.1136/annrheumdis-2017-212614. Epub 2018 Mar 7. Ann Rheum Dis. 2018. PMID: 29514802 Free PMC article.
31 results