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Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance.
Martins A, Judák F, Farkas Z, Szili P, Grézal G, Csörgő B, Czikkely MS, Maharramov E, Daruka L, Spohn R, Balogh D, Daraba A, Juhász S, Vágvölgyi M, Hunyadi A, Cao Y, Sun Z, Li X, Papp B, Pál C. Martins A, et al. Among authors: maharramov e. Sci Transl Med. 2025 Jan 8;17(780):eadl2103. doi: 10.1126/scitranslmed.adl2103. Epub 2025 Jan 8. Sci Transl Med. 2025. PMID: 39772773
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus.
Durcik M, Cotman AE, Toplak Ž, Možina Š, Skok Ž, Szili PE, Czikkely M, Maharramov E, Vu TH, Piras MV, Zidar N, Ilaš J, Zega A, Trontelj J, Pardo LA, Hughes D, Huseby D, Berruga-Fernández T, Cao S, Simoff I, Svensson R, Korol SV, Jin Z, Vicente F, Ramos MC, Mundy JEA, Maxwell A, Stevenson CEM, Lawson DM, Glinghammar B, Sjöström E, Bohlin M, Oreskär J, Alvér S, Janssen GV, Sterk GJ, Kikelj D, Pal C, Tomašič T, Peterlin Mašič L. Durcik M, et al. Among authors: maharramov e. J Med Chem. 2023 Mar 23;66(6):3968-3994. doi: 10.1021/acs.jmedchem.2c01905. Epub 2023 Mar 6. J Med Chem. 2023. PMID: 36877255 Free PMC article.