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Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin.
Williams JN, Irwin M, Li Y, Kambrath AV, Mattingly BT, Patel S, Kittaka M, Collins RN, Clough NA, Doud EH, Mosley AL, Bellido T, Bruzzaniti A, Plotkin LI, Trinidad JC, Thompson WR, Bonewald LF, Sankar U. Williams JN, et al. Among authors: kambrath av. Int J Mol Sci. 2023 Mar 1;24(5):4718. doi: 10.3390/ijms24054718. Int J Mol Sci. 2023. PMID: 36902150 Free PMC article.
Systemic inhibition or global deletion of CaMKK2 protects against post-traumatic osteoarthritis.
Mével E, Shutter JA, Ding X, Mattingly BT, Williams JN, Li Y, Huls A, Kambrath AV, Trippel SB, Wagner D, Allen MR, O'Keefe R, Thompson WR, Burr DB, Sankar U. Mével E, et al. Among authors: kambrath av. Osteoarthritis Cartilage. 2022 Jan;30(1):124-136. doi: 10.1016/j.joca.2021.09.001. Epub 2021 Sep 17. Osteoarthritis Cartilage. 2022. PMID: 34506942 Free PMC article.
Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification.
Williams JN, Kambrath AV, Patel RB, Kang KS, Mével E, Li Y, Cheng YH, Pucylowski AJ, Hassert MA, Voor MJ, Kacena MA, Thompson WR, Warden SJ, Burr DB, Allen MR, Robling AG, Sankar U. Williams JN, et al. Among authors: kambrath av. J Bone Miner Res. 2018 May;33(5):930-944. doi: 10.1002/jbmr.3379. Epub 2018 Feb 5. J Bone Miner Res. 2018. PMID: 29314250 Free PMC article.