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531 results

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Page 1
Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial.
Daix T, Mathonnet A, Brakenridge S, Dequin PF, Mira JP, Berbille F, Morre M, Jeannet R, Blood T, Unsinger J, Blood J, Walton A, Moldawer LL, Hotchkiss R, François B. Daix T, et al. Among authors: moldawer ll. Ann Intensive Care. 2023 Mar 12;13(1):17. doi: 10.1186/s13613-023-01109-w. Ann Intensive Care. 2023. PMID: 36906875 Free PMC article.
Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γELISpot: A Multicenter, Prospective Observational Study.
Barrios EA, Mazer MB, McGonagill P, Bergmann CB, Goodman MD, Gould R, Rao M, Polcz V, Davis R, Del Toro D, Dirain M, Dram A, Hale L, Heidarian M, Kucaba TA, Lanz JP, McCray A, Meszaros S, Miles S, Nelson C, Rocha I, Silva EE, Ungaro R, Walton A, Xu J, Zeumer-Spataro L, Drewry A, Liang M, Bible LE, Loftus T, Turnbull I, Efron PA, Remy KE, Brakenridge S, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EA, et al. Among authors: moldawer ll. medRxiv [Preprint]. 2023 Sep 24:2023.09.13.23295360. doi: 10.1101/2023.09.13.23295360. medRxiv. 2023. Update in: JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785 PMID: 37745385 Free PMC article. Updated. Preprint.
Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot.
Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Davis RJ, Del Toro DE, Dirain ML, Dram A, Hale LO, Heidarian M, Kim CY, Kucaba TA, Lanz JP, McCray AE, Meszaros S, Miles S, Nelson CR, Rocha IL, Silva EE, Ungaro RF, Walton AH, Xu J, Zeumer-Spataro L, Drewry AM, Liang M, Bible LE, Loftus TJ, Turnbull IR, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EL, et al. Among authors: moldawer ll. JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785. JCI Insight. 2024. PMID: 38100268 Free PMC article.
TEMPORAL CHANGES IN INNATE AND ADAPTIVE IMMUNITY DURING SEPSIS AS DETERMINED BY ELISPOT.
Unsinger J, Osborne D, Walton AH, Han E, Sheets L, Mazer MB, Remy KE, Griffith TS, Rao M, Badovinac VP, Brakenridge SC, Turnbull I, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS. Unsinger J, et al. Among authors: moldawer ll. Shock. 2024 Aug 1;62(2):255-264. doi: 10.1097/SHK.0000000000002377. Epub 2024 May 3. Shock. 2024. PMID: 38754032
Development and optimization of a diluted whole blood ELISpot assay to test immune function.
Ungaro RF, Xu J, Kucaba TA, Rao M, Bergmann CB, Brakenridge SC, Efron PA, Goodman MD, Gould RW, Hotchkiss RS, Liang M, Mazer MB, McGonagill PW, Moldawer LL, Remy KE, Turnbull IR, Caldwell CC, Badovinac VP, Griffith TS. Ungaro RF, et al. Among authors: moldawer ll. J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743. Epub 2024 Aug 13. J Immunol Methods. 2024. PMID: 39147231 Free article.
Severe trauma leads to sustained muscle loss, induced frailty, and distinct temporal changes in myokine and chemokine profiles of older patients.
Polcz VE, Barrios EL, Cox MC, Rocha I, Liang M, Hawkins RB, Darden D, Ungaro R, Dirain M, Mankowski R, Mohr AM, Moore FA, Moldawer LL, Efron PA, Brakenridge SC, Loftus TJ. Polcz VE, et al. Among authors: moldawer ll. Surgery. 2024 Nov;176(5):1516-1524. doi: 10.1016/j.surg.2024.07.031. Epub 2024 Aug 22. Surgery. 2024. PMID: 39179433
Defining critical illness using immunological endotypes in patients with and without of sepsis: A cohort study.
Balch JA, Chen UI, Liesenfeld O, Starostik P, Loftus TJ, Efron PA, Brakenridge SC, Sweeney TE, Moldawer LL. Balch JA, et al. Among authors: moldawer ll. Res Sq [Preprint]. 2023 May 8:rs.3.rs-2874506. doi: 10.21203/rs.3.rs-2874506/v1. Res Sq. 2023. Update in: Crit Care. 2023 Jul 20;27(1):292. doi: 10.1186/s13054-023-04571-x PMID: 37214996 Free PMC article. Updated. Preprint.
Temporal Changes in Innate and Adaptive Immunity During Sepsis as Determined by ELISpot.
Unsinger J, Osborne D, Walton AH, Han E, Sheets L, Mazer MB, Remy KE, Griffith TS, Rao M, Badovinac VP, Brackenridge SC, Turnbull I, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS. Unsinger J, et al. Among authors: moldawer ll. bioRxiv [Preprint]. 2023 Dec 14:2023.12.14.571668. doi: 10.1101/2023.12.14.571668. bioRxiv. 2023. Update in: Shock. 2024 Aug 1;62(2):255-264. doi: 10.1097/SHK.0000000000002377 PMID: 38168302 Free PMC article. Updated. Preprint.
TRANSCRIPTOMIC DIFFERENCES IN PERIPHERAL MONOCYTE POPULATIONS IN SEPTIC PATIENTS BASED ON OUTCOME.
Barrios EL, Rincon JC, Willis M, Polcz VE, Leary JR, Darden DB, Balch JA, Larson SD, Loftus TJ, Mohr AM, Wallet S, Brusko MA, Balzano-Nogueira L, Cai G, Sharma A, Upchurch GR Jr, Kladde MP, Mathews CE, Maile R, Moldawer LL, Bacher R, Efron PA. Barrios EL, et al. Among authors: moldawer ll. Shock. 2024 Aug 1;62(2):208-216. doi: 10.1097/SHK.0000000000002379. Epub 2024 May 2. Shock. 2024. PMID: 38713581
531 results