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Efficacy of Osimertinib in Patients with Lung Cancer Positive for Uncommon EGFR Exon 19 Deletion Mutations.
Clin Cancer Res. 2023 Jun 1;29(11):2123-2130. doi: 10.1158/1078-0432.CCR-22-3497.
Clin Cancer Res. 2023.
PMID: 36913537
Free PMC article.
Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations.
van Alderwerelt van Rosenburgh IK, Lu DM, Grant MJ, Stayrook SE, Phadke M, Walther Z, Goldberg SB, Politi K, Lemmon MA, Ashtekar KD, Tsutsui Y.
van Alderwerelt van Rosenburgh IK, et al.
Nat Commun. 2022 Nov 10;13(1):6791. doi: 10.1038/s41467-022-34398-z.
Nat Commun. 2022.
PMID: 36357385
Free PMC article.
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Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics.
Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, Lemmon MA.
Kiyatkin A, et al. Among authors: van alderwerelt van rosenburgh ik.
Sci Signal. 2020 Aug 18;13(645):eaaz5267. doi: 10.1126/scisignal.aaz5267.
Sci Signal. 2020.
PMID: 32817373
Free PMC article.
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Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations.
Starrett JH, Guernet AA, Cuomo ME, Poels KE, van Alderwerelt van Rosenburgh IK, Nagelberg A, Farnsworth D, Price KS, Khan H, Ashtekar KD, Gaefele M, Ayeni D, Stewart TF, Kuhlmann A, Kaech SM, Unni AM, Homer R, Lockwood WW, Michor F, Goldberg SB, Lemmon MA, Smith PD, Cross DAE, Politi K.
Starrett JH, et al. Among authors: van alderwerelt van rosenburgh ik.
Cancer Res. 2020 May 15;80(10):2017-2030. doi: 10.1158/0008-5472.CAN-19-3819. Epub 2020 Mar 19.
Cancer Res. 2020.
PMID: 32193290
Free PMC article.
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