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Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
Gottschlich A, Thomas M, Grünmeier R, Lesch S, Rohrbacher L, Igl V, Briukhovetska D, Benmebarek MR, Vick B, Dede S, Müller K, Xu T, Dhoqina D, Märkl F, Robinson S, Sendelhofert A, Schulz H, Umut Ö, Kavaka V, Tsiverioti CA, Carlini E, Nandi S, Strzalkowski T, Lorenzini T, Stock S, Müller PJ, Dörr J, Seifert M, Cadilha BL, Brabenec R, Röder N, Rataj F, Nüesch M, Modemann F, Wellbrock J, Fiedler W, Kellner C, Beltrán E, Herold T, Paquet D, Jeremias I, von Baumgarten L, Endres S, Subklewe M, Marr C, Kobold S. Gottschlich A, et al. Among authors: kellner c. Nat Biotechnol. 2023 Nov;41(11):1618-1632. doi: 10.1038/s41587-023-01684-0. Epub 2023 Mar 13. Nat Biotechnol. 2023. PMID: 36914885 Free PMC article.
Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab.
Baumann N, Arndt C, Petersen J, Lustig M, Rösner T, Klausz K, Kellner C, Bultmann M, Bastian L, Vogiatzi F, Leusen JHW, Burger R, Schewe DM, Peipp M, Valerius T. Baumann N, et al. Among authors: kellner c. Front Immunol. 2022 Aug 16;13:949140. doi: 10.3389/fimmu.2022.949140. eCollection 2022. Front Immunol. 2022. PMID: 36052078 Free PMC article.
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
Zeller T, Lutz S, Münnich IA, Windisch R, Hilger P, Herold T, Tahiri N, Banck JC, Weigert O, Moosmann A, von Bergwelt-Baildon M, Flamann C, Bruns H, Wichmann C, Baumann N, Valerius T, Schewe DM, Peipp M, Rösner T, Humpe A, Kellner C. Zeller T, et al. Among authors: kellner c. Front Immunol. 2022 Oct 27;13:929339. doi: 10.3389/fimmu.2022.929339. eCollection 2022. Front Immunol. 2022. PMID: 36389667 Free PMC article.
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
Windisch R, Soliman S, Hoffmann A, Chen-Wichmann L, Danese A, Vosberg S, Bravo J, Lutz S, Kellner C, Fischer A, Gebhard C, Redondo Monte E, Hartmann L, Schneider S, Beier F, Strobl CD, Weigert O, Peipp M, Schündeln M, Stricker SH, Rehli M, Bernhagen J, Humpe A, Klump H, Brendel C, Krause DS, Greif PA, Wichmann C. Windisch R, et al. Among authors: kellner c. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2312499121. doi: 10.1073/pnas.2312499121. Epub 2024 Jun 10. Proc Natl Acad Sci U S A. 2024. PMID: 38857395 Free PMC article.
Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo.
Winterberg D, Lenk L, Oßwald M, Vogiatzi F, Gehlert CL, Frielitz FS, Klausz K, Rösner T, Valerius T, Trauzold A, Peipp M, Kellner C, Schewe DM. Winterberg D, et al. Among authors: kellner c. J Clin Med. 2021 Jun 15;10(12):2634. doi: 10.3390/jcm10122634. J Clin Med. 2021. PMID: 34203833 Free PMC article.
Enhanced potency of immunotherapy against B-cell precursor acute lymphoblastic leukemia by combination of an Fc-engineered CD19 antibody and CD47 blockade.
Schewe DM, Vogiatzi F, Münnich IA, Zeller T, Windisch R, Wichmann C, Müller K, Bhat H, Felix E, Mougiakakos D, Bruns H, Lenk L, Valerius T, Humpe A, Peipp M, Kellner C. Schewe DM, et al. Among authors: kellner c. Hemasphere. 2024 Feb 22;8(2):e48. doi: 10.1002/hem3.48. eCollection 2024 Feb. Hemasphere. 2024. PMID: 38435424 Free PMC article.
698 results