Tsai YL - Search Results

1

A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.

Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. Lo WL, et al. Among authors: tsai yl. Nat Immunol. 2023 Apr;24(4):676-689. doi: 10.1038/s41590-023-01444-x. Epub 2023 Mar 13. Nat Immunol. 2023. PMID: 36914891 Free PMC article.

2

TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.

Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A. Tsai YL, et al. Immunity. 2023 Dec 12;56(12):2682-2698.e9. doi: 10.1016/j.immuni.2023.11.010. Immunity. 2023. PMID: 38091950 Free PMC article.

3

Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling.

Tsai YL, Ha DP, Zhao H, Carlos AJ, Wei S, Pun TK, Wu K, Zandi E, Kelly K, Lee AS. Tsai YL, et al. Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4245-E4254. doi: 10.1073/pnas.1714866115. Epub 2018 Apr 13. Proc Natl Acad Sci U S A. 2018. PMID: 29654145 Free PMC article.

4

ER residential chaperone GRP78 unconventionally relocalizes to the cell surface via endosomal transport.

Van Krieken R, Tsai YL, Carlos AJ, Ha DP, Lee AS. Van Krieken R, et al. Among authors: tsai yl. Cell Mol Life Sci. 2021 Jun;78(12):5179-5195. doi: 10.1007/s00018-021-03849-z. Epub 2021 May 11. Cell Mol Life Sci. 2021. PMID: 33974094 Free PMC article.

5

Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.

Ha DP, Tsai YL, Lee AS. Ha DP, et al. Among authors: tsai yl. Neoplasia. 2021 Dec;23(12):1213-1226. doi: 10.1016/j.neo.2021.10.004. Epub 2021 Nov 9. Neoplasia. 2021. PMID: 34768108 Free PMC article.

6

Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production.

Zhang Y, Tseng CC, Tsai YL, Fu X, Schiff R, Lee AS. Zhang Y, et al. Among authors: tsai yl. PLoS One. 2013 Nov 11;8(11):e80071. doi: 10.1371/journal.pone.0080071. eCollection 2013. PLoS One. 2013. PMID: 24244613 Free PMC article.

7

Inducing phospholipase A2 and cyclooxygenase-2 expression and prostaglandins' production of human dental pulp cells by activation of NOD receptor and its downstream signaling.

Chang MC, Chang SH, Tsai YL, Pan YH, Yeung SY, Chang HH, Jeng JH. Chang MC, et al. Among authors: tsai yl. Int J Biol Macromol. 2024 Dec 25;292:139193. doi: 10.1016/j.ijbiomac.2024.139193. Online ahead of print. Int J Biol Macromol. 2024. PMID: 39730047

8

Pyr3 inhibits cell viability and PKCα activity to suppress migration in human bladder cancer cells.

Ting HK, Dou YC, Lin YH, Chen TM, Tsai YL, Tsai WC, Wu ST, Chen Y. Ting HK, et al. Among authors: tsai yl. Eur J Pharmacol. 2024 Dec 24;988:177235. doi: 10.1016/j.ejphar.2024.177235. Online ahead of print. Eur J Pharmacol. 2024. PMID: 39725132

9

A Roadmap of Peptide-Based Materials in Neural Regeneration.

Tsai YL, Song J, Shi R, Knöll B, Synatschke CV. Tsai YL, et al. Adv Healthc Mater. 2024 Nov 14:e2402939. doi: 10.1002/adhm.202402939. Online ahead of print. Adv Healthc Mater. 2024. PMID: 39540310 Review.

10

Enhancing medical students' understanding of end-of-life care ethics and law through video-triggered expert-led debriefing: a two-stage study.

Chao YP, Tsai YL, Ng DY, Liaw JJ, Fu CP, Wang CC. Chao YP, et al. Among authors: tsai yl. BMC Med Educ. 2024 Nov 9;24(1):1285. doi: 10.1186/s12909-024-06304-2. BMC Med Educ. 2024. PMID: 39522007 Free PMC article.

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