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Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling.
Saber S, El-Fattah EEA, Abdelhamid AM, Mourad AAE, Hamouda MAM, Elrabat A, Zakaria S, Haleem AA, Mohamed SZ, Elgharabawy RM, Morsy NE, El Adle Khalaf N, Mohammed OA, El-Bahouty WB, Mostafa SA, Abdelhady R, Galal O, ElSaid ZH, Yahya G, Shata A, Youssef ME. Saber S, et al. Among authors: shata a. Biomed Pharmacother. 2023 Feb;158:114196. doi: 10.1016/j.biopha.2022.114196. Epub 2023 Jan 2. Biomed Pharmacother. 2023. PMID: 36916405 Free article.
A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition.
Saber S, Abd El-Fattah EE, Yahya G, Gobba NA, Maghmomeh AO, Khodir AE, Mourad AAE, Saad AS, Mohammed HG, Nouh NA, Shata A, Amin NA, Abou El-Rous M, Girgis S, El-Ahwany E, Khalaf EM, El-Kott AF, El-Baz AM. Saber S, et al. Among authors: shata a. Pharmaceuticals (Basel). 2021 Apr 8;14(4):341. doi: 10.3390/ph14040341. Pharmaceuticals (Basel). 2021. PMID: 33917884 Free PMC article.
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression.
Saber S, Nasr M, Saad AS, Mourad AAE, Gobba NA, Shata A, Hafez AM, Elsergany RN, Elagamy HI, El-Ahwany E, Amin NA, Girgis S, Elewa YHA, Mahmoud MH, Batiha GE, El-Rous MA, Kamal I, Kaddah MMY, Khodir AE. Saber S, et al. Among authors: shata a. Biomed Pharmacother. 2021 Oct;142:112029. doi: 10.1016/j.biopha.2021.112029. Epub 2021 Aug 17. Biomed Pharmacother. 2021. PMID: 34416629 Free article.
Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride.
Abdelhamid AM, Youssef ME, Abd El-Fattah EE, Gobba NA, Gaafar AGA, Girgis S, Shata A, Hafez AM, El-Ahwany E, Amin NA, Shahien MA, Abd-Eldayem MA, Abou-Elrous M, Saber S. Abdelhamid AM, et al. Among authors: shata a. Life Sci. 2021 Dec 1;286:120070. doi: 10.1016/j.lfs.2021.120070. Epub 2021 Oct 21. Life Sci. 2021. PMID: 34688695
The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury.
Abd El-Fattah EE, Saber S, Mourad AAE, El-Ahwany E, Amin NA, Cavalu S, Yahya G, Saad AS, Alsharidah M, Shata A, Sami HM, Kaddah MMY, Ghanim AMH. Abd El-Fattah EE, et al. Among authors: shata a. Biomed Pharmacother. 2022 Mar;147:112628. doi: 10.1016/j.biopha.2022.112628. Epub 2022 Jan 12. Biomed Pharmacother. 2022. PMID: 35032769 Free article.
Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need.
Zohny MH, Cavalu S, Youssef ME, Kaddah MMY, Mourad AAE, Gaafar AGA, El-Ahwany E, Amin NA, Arakeep HM, Shata A, Saleh S, Hafez MM, Elazab ST, Abdelhady R, El Shahat RM, Yahya G, Saber S. Zohny MH, et al. Among authors: shata a. Biomed Pharmacother. 2022 Apr;148:112723. doi: 10.1016/j.biopha.2022.112723. Epub 2022 Feb 21. Biomed Pharmacother. 2022. PMID: 35202914 Free article.
Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs.
Saber S, Nasr M, Kaddah MMY, Mostafa-Hedeab G, Cavalu S, Mourad AAE, Gaafar AGA, Zaghlool SS, Saleh S, Hafez MM, Girgis S, Elgharabawy RM, Nader K, Alsharidah M, Batiha GE, El-Ahwany E, Amin NA, Elagamy HI, Shata A, Nader R, Khodir AE. Saber S, et al. Among authors: shata a. Biomed Pharmacother. 2022 Apr;148:112731. doi: 10.1016/j.biopha.2022.112731. Epub 2022 Feb 24. Biomed Pharmacother. 2022. PMID: 35220029 Free article.
44 results