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CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.
Paust HJ, Song N, De Feo D, Asada N, Tuzlak S, Zhao Y, Riedel JH, Hellmig M, Sivayoganathan A, Peters A, Kaffke A, Borchers A, Wenzel UO, Steinmetz OM, Tiegs G, Meister E, Mack M, Kurts C, von Vietinghoff S, Lindenmeyer MT, Hoxha E, Stahl RAK, Huber TB, Bonn S, Meyer-Schwesinger C, Wiech T, Turner JE, Becher B, Krebs CF, Panzer U. Paust HJ, et al. Among authors: riedel jh. Sci Transl Med. 2023 Mar 15;15(687):eadd6137. doi: 10.1126/scitranslmed.add6137. Epub 2023 Mar 15. Sci Transl Med. 2023. PMID: 36921033
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.
Turner JE, Paust HJ, Steinmetz OM, Peters A, Riedel JH, Erhardt A, Wegscheid C, Velden J, Fehr S, Mittrücker HW, Tiegs G, Stahl RA, Panzer U. Turner JE, et al. Among authors: riedel jh. J Am Soc Nephrol. 2010 Jun;21(6):974-85. doi: 10.1681/ASN.2009070741. Epub 2010 Mar 18. J Am Soc Nephrol. 2010. PMID: 20299360 Free PMC article.
CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.
Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U. Paust HJ, et al. Among authors: riedel jh. J Am Soc Nephrol. 2016 Jul;27(7):1933-42. doi: 10.1681/ASN.2015020203. Epub 2015 Nov 3. J Am Soc Nephrol. 2016. PMID: 26534920 Free PMC article.
IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases.
Riedel JH, Paust HJ, Krohn S, Turner JE, Kluger MA, Steinmetz OM, Krebs CF, Stahl RA, Panzer U. Riedel JH, et al. J Am Soc Nephrol. 2016 Dec;27(12):3666-3677. doi: 10.1681/ASN.2015101077. Epub 2016 Mar 30. J Am Soc Nephrol. 2016. PMID: 27030744 Free PMC article.
Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney.
Krebs CF, Paust HJ, Krohn S, Koyro T, Brix SR, Riedel JH, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch P, Mittrücker HW, Steinhoff U, Stockinger B, Perez LG, Wenzel UO, Janneck M, Steinmetz OM, Gagliani N, Stahl RAK, Huber S, Turner JE, Panzer U. Krebs CF, et al. Among authors: riedel jh. Immunity. 2016 Nov 15;45(5):1078-1092. doi: 10.1016/j.immuni.2016.10.020. Immunity. 2016. PMID: 27851911 Free PMC article.
T helper type 17 cells in immune-mediated glomerular disease.
Krebs CF, Schmidt T, Riedel JH, Panzer U. Krebs CF, et al. Among authors: riedel jh. Nat Rev Nephrol. 2017 Oct;13(10):647-659. doi: 10.1038/nrneph.2017.112. Epub 2017 Aug 7. Nat Rev Nephrol. 2017. PMID: 28781371 Review.
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