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Population pharmacokinetics and exposure-response analysis of a single dose of sotrovimab in the early treatment of patients with mild to moderate COVID-19.
Sager JE, El-Zailik A, Passarell J, Roepcke S, Li X, Aldinger M, Nader A, Skingsley A, Alexander EL, Yeh WW, Mogalian E, Garner C, Peppercorn A, Shapiro AE, Reyes M. Sager JE, et al. Among authors: passarell j. CPT Pharmacometrics Syst Pharmacol. 2023 Jun;12(6):853-864. doi: 10.1002/psp4.12958. Epub 2023 Apr 6. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36922886 Free PMC article.
Challenges in the transition to model-based development.
Grasela TH, Fiedler-Kelly J, Walawander CA, Owen JS, Cirincione BB, Reitz KE, Ludwig EA, Passarell JA, Dement CW. Grasela TH, et al. Among authors: passarell ja. AAPS J. 2005 Oct 5;7(2):E488-95. doi: 10.1208/aapsj070249. AAPS J. 2005. PMID: 16353926 Free PMC article. Review.
Tedizolid population pharmacokinetics, exposure response, and target attainment.
Flanagan S, Passarell J, Lu Q, Fiedler-Kelly J, Ludwig E, Prokocimer P. Flanagan S, et al. Among authors: passarell j. Antimicrob Agents Chemother. 2014 Nov;58(11):6462-70. doi: 10.1128/AAC.03423-14. Epub 2014 Aug 18. Antimicrob Agents Chemother. 2014. PMID: 25136028 Free PMC article.
Exposure-safety and efficacy response relationships and population pharmacokinetics of eslicarbazepine acetate.
Gidal BE, Jacobson MP, Ben-Menachem E, Carreño M, Blum D, Soares-da-Silva P, Falcão A, Rocha F, Moreira J, Grinnell T, Ludwig E, Fiedler-Kelly J, Passarell J, Sunkaraneni S. Gidal BE, et al. Among authors: passarell j. Acta Neurol Scand. 2018 Sep;138(3):203-211. doi: 10.1111/ane.12950. Epub 2018 May 6. Acta Neurol Scand. 2018. PMID: 29732549 Free PMC article. Clinical Trial.
Pharmacokinetic-pharmacodynamic (dipeptidyl peptidase-4 inhibition) model to support dose rationale in diabetes patients, including those with renal impairment, for once-weekly administered omarigliptin.
Jain L, Chain ASY, Tatosian DA, Hing J, Passarell JA, Kauh EA, Lai E. Jain L, et al. Among authors: passarell ja. Br J Clin Pharmacol. 2019 Dec;85(12):2759-2771. doi: 10.1111/bcp.14103. Epub 2019 Dec 9. Br J Clin Pharmacol. 2019. PMID: 31454094 Free PMC article.
38 results