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Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Zecha J, Bayer FP, Wiechmann S, Woortman J, Berner N, Müller J, Schneider A, Kramer K, Abril-Gil M, Hopf T, Reichart L, Chen L, Hansen FM, Lechner S, Samaras P, Eckert S, Lautenbacher L, Reinecke M, Hamood F, Prokofeva P, Vornholz L, Falcomatà C, Dorsch M, Schröder A, Venhuizen A, Wilhelm S, Médard G, Stoehr G, Ruland J, Grüner BM, Saur D, Buchner M, Ruprecht B, Hahne H, The M, Wilhelm M, Kuster B. Zecha J, et al. Among authors: wilhelm m, wilhelm s. Science. 2023 Apr 7;380(6640):93-101. doi: 10.1126/science.ade3925. Epub 2023 Mar 16. Science. 2023. PMID: 36926954 Free PMC article.
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition.
Kücükdisli M, Bel-Abed H, Cirillo D, Lo WT, Efrém NL, Horatscheck A, Perepelittchenko L, Prokofeva P, Ehret TAL, Radetzki S, Neuenschwander M, Specker E, Médard G, Müller S, Wilhelm S, Kuster B, von Kries JP, Haucke V, Nazaré M. Kücükdisli M, et al. Among authors: wilhelm s. J Med Chem. 2023 Oct 26;66(20):14278-14302. doi: 10.1021/acs.jmedchem.3c01319. Epub 2023 Oct 11. J Med Chem. 2023. PMID: 37819647 Free PMC article.
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B. Reinecke M, et al. Among authors: wilhelm m, wilhelm s. Nat Chem Biol. 2024 May;20(5):577-585. doi: 10.1038/s41589-023-01459-3. Epub 2023 Oct 30. Nat Chem Biol. 2024. PMID: 37904048 Free PMC article.
Recurring incursions and dissemination of novel Eurasian-origin H5Nx avian influenza viruses in Atlantic Canada.
Rahman I, Erdelyan CNG, Signore AV, Ayilara I, Wight J, Jones MEB, Sullivan DS, Lung O, Hisanaga T, Wilhelm SI, Cunningham JT, Ward CRE, Bosch J, Robertson GJ, Gosse K, Baker M, Dawe B, Lair S, Provencher JF, Hargan KE, Berhane Y, Lang AS. Rahman I, et al. Among authors: wilhelm si. Virus Evol. 2024 Dec 17;10(1):veae111. doi: 10.1093/ve/veae111. eCollection 2024. Virus Evol. 2024. PMID: 39722685 Free PMC article.
Molecular investigation of harmful cyanobacteria reveals hidden risks and niche partitioning in Kenyan Lakes.
Zepernick BN, Hart LN, Chase EE, Natwora KE, Obuya JA, Olokotum M, Houghton KA, Kiledal EA; NSF-IRES 2022 Lake Victoria Research Consortium; Sheik CS, Sherman DH, Dick GJ, Wilhelm SW, Sitoki L, Otiso KM, McKay RML, Bullerjahn GS. Zepernick BN, et al. Among authors: wilhelm sw. Harmful Algae. 2024 Dec;140:102757. doi: 10.1016/j.hal.2024.102757. Epub 2024 Nov 10. Harmful Algae. 2024. PMID: 39613370 Free article.
937 results