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Corrigendum to 'Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand': Journal of Thrombosis and Haemostasis, Volume 22, Issue 1, (January 2024) Pages 271-285.
Martin EM, Clark JC, Montague SJ, Morán LA, Di Y, Bull LJ, Whittle L, Raka F, Buka RJ, Zafar I, Kardeby C, Slater A, Watson SP. Martin EM, et al. Among authors: clark jc. J Thromb Haemost. 2024 Aug;22(8):2378-2379. doi: 10.1016/j.jtha.2024.06.001. Epub 2024 Jun 20. J Thromb Haemost. 2024. PMID: 38902124 Free article. No abstract available.
Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand.
Martin EM, Clark JC, Montague SJ, Morán LA, Di Y, Bull LJ, Whittle L, Raka F, Buka RJ, Zafar I, Kardeby C, Slater A, Watson SP. Martin EM, et al. Among authors: clark jc. J Thromb Haemost. 2024 Jan;22(1):271-285. doi: 10.1016/j.jtha.2023.09.026. Epub 2023 Oct 9. J Thromb Haemost. 2024. PMID: 37813196 Free article.
Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists.
Clark JC, Martin EM, Morán LA, Di Y, Wang X, Zuidscherwoude M, Brown HC, Kavanagh DM, Hummert J, Eble JA, Nieswandt B, Stegner D, Pollitt AY, Herten DP, Tomlinson MG, García A, Watson SP. Clark JC, et al. Commun Biol. 2023 Apr 7;6(1):376. doi: 10.1038/s42003-023-04766-6. Commun Biol. 2023. PMID: 37029319 Free PMC article.
Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.
Damaskinaki FN, Jooss NJ, Martin EM, Clark JC, Thomas MR, Poulter NS, Emsley J, Kellam B, Watson SP, Slater A. Damaskinaki FN, et al. Among authors: clark jc. J Thromb Haemost. 2023 Feb;21(2):317-328. doi: 10.1016/j.jtha.2022.11.002. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36700508 Free article.
274 results