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Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis.
Shkhyan R, Flynn C, Lamoure E, Sarkar A, Van Handel B, Li J, York J, Banks N, Van der Horst R, Liu NQ, Lee S, Bajaj P, Vadivel K, Harn HI, Tassey J, Lozito T, Lieberman JR, Chuong CM, Hurtig MS, Evseenko D. Shkhyan R, et al. Among authors: lozito t. Sci Transl Med. 2023 Mar 22;15(688):eabq2395. doi: 10.1126/scitranslmed.abq2395. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947594 Free PMC article.
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Liu X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW. Cui C, et al. Among authors: lozito tp. PLoS Biol. 2013 Nov;11(11):e1001720. doi: 10.1371/journal.pbio.1001720. Epub 2013 Nov 26. PLoS Biol. 2013. PMID: 24302887 Free PMC article.
30 results