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Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity.
Dos Santos NSA, Estevez-Castro CF, Macedo JP, Chame DF, Castro-Gomes T, Santos-Cardoso M, Burle-Caldas GA, Covington CN, Steel PG, Smith TK, Denny PW, Teixeira SMR. Dos Santos NSA, et al. Among authors: denny pw. PLoS Negl Trop Dis. 2023 Sep 20;17(9):e0011646. doi: 10.1371/journal.pntd.0011646. eCollection 2023 Sep. PLoS Negl Trop Dis. 2023. PMID: 37729272 Free PMC article.
Evaluation of the Leishmania Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach.
Alpizar-Sosa EA, Zimbres FM, Mantilla BS, Dickie EA, Wei W, Burle-Caldas GA, Filipe LNS, Van Bocxlaer K, Price HP, Ibarra-Meneses AV, Beaudry F, Fernandez-Prada C, Whitfield PD, Barrett MP, Denny PW. Alpizar-Sosa EA, et al. Among authors: denny pw. ACS Infect Dis. 2024 Aug 9;10(8):2913-2928. doi: 10.1021/acsinfecdis.4c00284. Epub 2024 Jul 18. ACS Infect Dis. 2024. PMID: 39023360 Free PMC article.
Genome deletions to overcome the directed loss of gene function in Leishmania.
Alpizar-Sosa EA, Kumordzi Y, Wei W, Whitfield PD, Barrett MP, Denny PW. Alpizar-Sosa EA, et al. Among authors: denny pw. Front Cell Infect Microbiol. 2022 Sep 23;12:988688. doi: 10.3389/fcimb.2022.988688. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36211960 Free PMC article.
70 results