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STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma.
Zhang P, Rashidi A, Zhao J, Silvers C, Wang H, Castro B, Ellingwood A, Han Y, Lopez-Rosas A, Zannikou M, Dmello C, Levine R, Xiao T, Cordero A, Sonabend AM, Balyasnikova IV, Lee-Chang C, Miska J, Lesniak MS. Zhang P, et al. Among authors: lopez rosas a. Nat Commun. 2023 Mar 23;14(1):1610. doi: 10.1038/s41467-023-37328-9. Nat Commun. 2023. PMID: 36959214 Free PMC article.
Myeloid-Derived Suppressive Cells Promote B cell-Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma.
Lee-Chang C, Rashidi A, Miska J, Zhang P, Pituch KC, Hou D, Xiao T, Fischietti M, Kang SJ, Appin CL, Horbinski C, Platanias LC, Lopez-Rosas A, Han Y, Balyasnikova IV, Lesniak MS. Lee-Chang C, et al. Among authors: lopez rosas a. Cancer Immunol Res. 2019 Dec;7(12):1928-1943. doi: 10.1158/2326-6066.CIR-19-0240. Epub 2019 Sep 17. Cancer Immunol Res. 2019. PMID: 31530559 Free PMC article.
Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma.
Zhang P, Miska J, Lee-Chang C, Rashidi A, Panek WK, An S, Zannikou M, Lopez-Rosas A, Han Y, Xiao T, Pituch KC, Kanojia D, Balyasnikova IV, Lesniak MS. Zhang P, et al. Among authors: lopez rosas a. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23714-23723. doi: 10.1073/pnas.1906346116. Epub 2019 Nov 11. Proc Natl Acad Sci U S A. 2019. PMID: 31712430 Free PMC article.
Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma.
Lee-Chang C, Miska J, Hou D, Rashidi A, Zhang P, Burga RA, Jusué-Torres I, Xiao T, Arrieta VA, Zhang DY, Lopez-Rosas A, Han Y, Sonabend AM, Horbinski CM, Stupp R, Balyasnikova IV, Lesniak MS. Lee-Chang C, et al. Among authors: lopez rosas a. J Exp Med. 2021 Jan 4;218(1):e20200913. doi: 10.1084/jem.20200913. J Exp Med. 2021. PMID: 32991668 Free PMC article.
GCN2 is essential for CD8+ T cell survival and function in murine models of malignant glioma.
Rashidi A, Miska J, Lee-Chang C, Kanojia D, Panek WK, Lopez-Rosas A, Zhang P, Han Y, Xiao T, Pituch KC, Kim JW, Talebian M, Fares J, Lesniak MS. Rashidi A, et al. Among authors: lopez rosas a. Cancer Immunol Immunother. 2020 Jan;69(1):81-94. doi: 10.1007/s00262-019-02441-6. Epub 2019 Dec 16. Cancer Immunol Immunother. 2020. PMID: 31844909 Free PMC article.
Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma.
Miska J, Rashidi A, Lee-Chang C, Gao P, Lopez-Rosas A, Zhang P, Burga R, Castro B, Xiao T, Han Y, Hou D, Sampat S, Cordero A, Stoolman JS, Horbinski CM, Burns M, Reshetnyak YK, Chandel NS, Lesniak MS. Miska J, et al. Among authors: lopez rosas a. Sci Adv. 2021 Feb 17;7(8):eabc8929. doi: 10.1126/sciadv.abc8929. Print 2021 Feb. Sci Adv. 2021. PMID: 33597238 Free PMC article.
26 results