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11,069 results

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Mutations in the B30.2 and the central helical scaffold domains of pyrin differentially affect inflammasome activation.
Chirita D, Bronnec P, Magnotti F, Dalmon S, Martin A, Popoff M, Gerfaud-Valentin M, Sève P, Belot A, Contis A, Duquesne A, Nocturne G, Lemelle I, Georgin-Lavialle S, Boursier G, Touitou I, Jamilloux Y, Henry T. Chirita D, et al. Among authors: martin a. Cell Death Dis. 2023 Mar 25;14(3):213. doi: 10.1038/s41419-023-05745-9. Cell Death Dis. 2023. PMID: 36966139 Free PMC article.
Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome.
Jamilloux Y, Lefeuvre L, Magnotti F, Martin A, Benezech S, Allatif O, Penel-Page M, Hentgen V, Sève P, Gerfaud-Valentin M, Duquesne A, Desjonquères M, Laurent A, Rémy-Piccolo V, Cimaz R, Cantarini L, Bourdonnay E, Walzer T, Py BF, Belot A, Henry T. Jamilloux Y, et al. Among authors: martin a. Rheumatology (Oxford). 2018 Jan 1;57(1):100-111. doi: 10.1093/rheumatology/kex373. Rheumatology (Oxford). 2018. PMID: 29040788
Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients.
Magnotti F, Lefeuvre L, Benezech S, Malsot T, Waeckel L, Martin A, Kerever S, Chirita D, Desjonqueres M, Duquesne A, Gerfaud-Valentin M, Laurent A, Sève P, Popoff MR, Walzer T, Belot A, Jamilloux Y, Henry T. Magnotti F, et al. Among authors: martin a. EMBO Mol Med. 2019 Nov 7;11(11):e10547. doi: 10.15252/emmm.201910547. Epub 2019 Oct 7. EMBO Mol Med. 2019. PMID: 31589380 Free PMC article.
Fast diagnostic test for familial Mediterranean fever based on a kinase inhibitor.
Magnotti F, Malsot T, Georgin-Lavialle S, Abbas F, Martin A, Belot A, Fauter M, Rabilloud M, Gerfaud-Valentin M, Sève P, Duquesne A, Hot A, Durupt S, Savey L, Giurgea I, Grateau G, Henry T, Jamilloux Y. Magnotti F, et al. Among authors: martin a. Ann Rheum Dis. 2021 Jan;80(1):128-132. doi: 10.1136/annrheumdis-2020-218366. Epub 2020 Oct 9. Ann Rheum Dis. 2021. PMID: 33037005
Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism.
Magnotti F, Chirita D, Dalmon S, Martin A, Bronnec P, Sousa J, Helynck O, Lee W, Kastner DL, Chae JJ, McDermott MF, Belot A, Popoff M, Sève P, Georgin-Lavialle S, Munier-Lehmann H, Tran TA, De Langhe E, Wouters C, Jamilloux Y, Henry T. Magnotti F, et al. Among authors: martin a. Cell Rep. 2022 Oct 11;41(2):111472. doi: 10.1016/j.celrep.2022.111472. Cell Rep. 2022. PMID: 36223753 Free PMC article.
IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.
Wallet P, Benaoudia S, Mosnier A, Lagrange B, Martin A, Lindgren H, Golovliov I, Michal F, Basso P, Djebali S, Provost A, Allatif O, Meunier E, Broz P, Yamamoto M, Py BF, Faudry E, Sjöstedt A, Henry T. Wallet P, et al. Among authors: martin a. PLoS Pathog. 2017 Oct 2;13(10):e1006630. doi: 10.1371/journal.ppat.1006630. eCollection 2017 Oct. PLoS Pathog. 2017. PMID: 28968459 Free PMC article.
A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells.
Benaoudia S, Martin A, Puig Gamez M, Gay G, Lagrange B, Cornut M, Krasnykov K, Claude JB, Bourgeois CF, Hughes S, Gillet B, Allatif O, Corbin A, Ricci R, Henry T. Benaoudia S, et al. Among authors: martin a. EMBO Rep. 2019 Sep;20(9):e48235. doi: 10.15252/embr.201948235. Epub 2019 Jul 29. EMBO Rep. 2019. PMID: 31353801 Free PMC article.
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