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Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer's and coronary disease pathways.
Wang L, Western D, Timsina J, Repaci C, Song WM, Norton J, Kohlfeld P, Budde J, Climer S, Butt OH, Jacobson D, Garvin M, Templeton AR, Campagna S, O'Halloran J, Presti R, Goss CW, Mudd PA, Ances BM, Zhang B, Sung YJ, Cruchaga C. Wang L, et al. iScience. 2023 Apr 21;26(4):106408. doi: 10.1016/j.isci.2023.106408. Epub 2023 Mar 14. iScience. 2023. PMID: 36974157 Free PMC article.
CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14.
Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari J, Pang APS, Sugai C, Mahyari E, Francisco EB, Pise A, Rodrigues H, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Bimber BN, Plassmeyer M, Gupta R, Alpan O, O'Halloran JA, Mudd PA, Akalin E, Ndhlovu LC, Sacha JB. Patterson BK, et al. Int J Infect Dis. 2021 Feb;103:25-32. doi: 10.1016/j.ijid.2020.10.101. Epub 2020 Nov 10. Int J Infect Dis. 2021. PMID: 33186704 Free PMC article.
Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm.
Mudd PA, Crawford JC, Turner JS, Souquette A, Reynolds D, Bender D, Bosanquet JP, Anand NJ, Striker DA, Martin RS, Boon ACM, House SL, Remy KE, Hotchkiss RS, Presti RM, O'Halloran JA, Powderly WG, Thomas PG, Ellebedy AH. Mudd PA, et al. Sci Adv. 2020 Dec 9;6(50):eabe3024. doi: 10.1126/sciadv.abe3024. Print 2020 Dec. Sci Adv. 2020. PMID: 33187979 Free PMC article.
SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans.
Turner JS, Kim W, Kalaidina E, Goss CW, Rauseo AM, Schmitz AJ, Hansen L, Haile A, Klebert MK, Pusic I, O'Halloran JA, Presti RM, Ellebedy AH. Turner JS, et al. Res Sq [Preprint]. 2020 Dec 31:rs.3.rs-132821. doi: 10.21203/rs.3.rs-132821/v1. Res Sq. 2020. Update in: Nature. 2021 Jul;595(7867):421-425. doi: 10.1038/s41586-021-03647-4 PMID: 33398264 Free PMC article. Updated. Preprint.
Interleukin-6 Trajectory and Secondary Infections in Mechanically Ventilated Patients With Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Treated With Interleukin-6 Receptor Blocker.
Vazquez Guillamet MC, Kulkarni HS, Montes K, Samant M, Shaikh PA, Betthauser K, Mudd PA, Reynolds D, O'Halloran J, Lyons P, McEvoy C, Vazquez Guillamet R. Vazquez Guillamet MC, et al. Crit Care Explor. 2021 Feb 3;3(2):e0343. doi: 10.1097/CCE.0000000000000343. eCollection 2021 Feb. Crit Care Explor. 2021. PMID: 33554125 Free PMC article.
225 results