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Page 1
EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.
Wolin AR, Vincent MY, Hotz T, Purdy SC, Rosenbaum SR, Hughes CJ, Hsu JY, Oliphant MUJ, Armstrong B, Wessells V, Varella-Garcia M, Galbraith MD, Pierce A, Wang D, Venkataraman S, Danis E, Veo B, Serkova N, Espinosa JM, Gustafson DL, Vibhakar R, Ford HL. Wolin AR, et al. Neuro Oncol. 2023 Dec 8;25(12):2287-2301. doi: 10.1093/neuonc/noad128. Neuro Oncol. 2023. PMID: 37486991 Free PMC article.
A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice.
Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jirón Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. Mills TS, et al. Cell Stem Cell. 2024 Nov 7;31(11):1630-1649.e8. doi: 10.1016/j.stem.2024.09.010. Epub 2024 Oct 15. Cell Stem Cell. 2024. PMID: 39413777
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma.
Hsieh J, Danis EP, Owens CR, Parrish JK, Nowling NL, Wolin AR, Purdy SC, Rosenbaum SR, Ivancevic AM, Chuong EB, Ford HL, Jedlicka P. Hsieh J, et al. Among authors: danis ep. Oncogene. 2025 Jan;44(1):19-29. doi: 10.1038/s41388-024-03201-2. Epub 2024 Oct 24. Oncogene. 2025. PMID: 39448867 Free PMC article.
SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma.
Hughes CJ, Fields KM, Danis EP, Hsu JY, Neelakantan D, Vincent MY, Gustafson AL, Oliphant MJ, Sreekanth V, Zaberezhnyy V, Costello JC, Jedlicka P, Ford HL. Hughes CJ, et al. Among authors: danis ep. Nat Commun. 2023 Jul 19;14(1):4357. doi: 10.1038/s41467-023-39945-w. Nat Commun. 2023. PMID: 37468459 Free PMC article.
GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia.
Alikarami F, Xie HM, Riedel SS, Goodrow H, Barrett DR, Mahdavi L, Lenard A, Chen C, Yamauchi T, Danis E, Cao Z, Tran VL, Jung MM, Li Y, Huang H, Shi J, Tan K, Teachey DT, Bresnick EH, Neff T, Bernt KM. Alikarami F, et al. Blood. 2025 Jan 22:blood.2024025761. doi: 10.1182/blood.2024025761. Online ahead of print. Blood. 2025. PMID: 39841459
MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity.
Boulton DP, Hughes CJ, Vaira V, Del Gobbo A, Palleschi A, Locatelli M, Danis E, Raza M, Neumann AJ, Purdy SC, Lerma R, Meshki J, Ford HL, Prekeris R, Morrissey C, Caino MC. Boulton DP, et al. Cell Rep. 2024 Dec 24;44(1):115120. doi: 10.1016/j.celrep.2024.115120. Online ahead of print. Cell Rep. 2024. PMID: 39723893 Free article.