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Page 1
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies.
Germon ZP, Sillar JR, Mannan A, Duchatel RJ, Staudt D, Murray HC, Findlay IJ, Jackson ER, McEwen HP, Douglas AM, McLachlan T, Schjenken JE, Skerrett-Byrne DA, Huang H, Melo-Braga MN, Plank MW, Alvaro F, Chamberlain J, De Iuliis G, Aitken RJ, Nixon B, Wei AH, Enjeti AK, Huang Y, Lock RB, Larsen MR, Lee H, Vaghjiani V, Cain JE, de Bock CE, Verrills NM, Dun MD. Germon ZP, et al. Among authors: de iuliis g. Sci Signal. 2023 Mar 28;16(778):eabp9586. doi: 10.1126/scisignal.abp9586. Epub 2023 Mar 28. Sci Signal. 2023. PMID: 36976863
Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.
Dun MD, Mannan A, Rigby CJ, Butler S, Toop HD, Beck D, Connerty P, Sillar J, Kahl RGS, Duchatel RJ, Germon Z, Faulkner S, Chi M, Skerrett-Byrne D, Murray HC, Flanagan H, Almazi JG, Hondermarck H, Nixon B, De Iuliis G, Chamberlain J, Alvaro F, de Bock CE, Morris JC, Enjeti AK, Verrills NM. Dun MD, et al. Among authors: de bock ce, de iuliis g. Leukemia. 2020 Dec;34(12):3393-3397. doi: 10.1038/s41375-020-0814-0. Epub 2020 Apr 8. Leukemia. 2020. PMID: 32269318 Free PMC article. No abstract available.
Subchronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice.
Trigg N, Schjenken JE, Martin JH, Skerrett-Byrne DA, Smyth SP, Bernstein IR, Anderson AL, Stanger SJ, Simpson ENA, Tomar A, Teperino R, Conine CC, De Iuliis GN, Roman SD, Bromfield EG, Dun MD, Eamens AL, Nixon B. Trigg N, et al. Among authors: de iuliis gn. Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2409790121. doi: 10.1073/pnas.2409790121. Epub 2024 Nov 11. Proc Natl Acad Sci U S A. 2024. PMID: 39527742
Assessment of the impact of direct in vitro PFAS treatment on mouse spermatozoa.
Calvert L, Martin JH, Anderson AL, Bernstein IR, Burke ND, De Iuliis GN, Eamens AL, Dun MD, Turner BD, Roman SD, Green MP, Nixon B. Calvert L, et al. Among authors: de iuliis gn. Reprod Fertil. 2024 Mar 8;5(1):e230087. doi: 10.1530/RAF-23-0087. Print 2024 Jan 1. Reprod Fertil. 2024. PMID: 38367345 Free PMC article.
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model.
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan WY, Davidson EA, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder EA, Coppi A, Schulz W, Iwasaki A, Pierce RW, Cruz CSD, Desir GV, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis NS, Ko AI; Yale IMPACT Study Team; Thompson DC, Vasiliou V. Charkoftaki G, et al. Hum Genomics. 2023 Aug 29;17(1):80. doi: 10.1186/s40246-023-00521-4. Hum Genomics. 2023. PMID: 37641126 Free PMC article.
SH2 Domain-Containing Phosphatase-SHP2 Attenuates Fibrotic Responses through Negative Regulation of Mitochondrial Metabolism in Lung Fibroblasts.
Karampitsakos T, Galaris A, Barbayianni I, DeIuliis G, Ahangari F, Sampsonas F, Sotiropoulou V, Aidinis V, Bennett AM, Herazo-Maya JD, Xylourgidis N, Bakakos P, Bouros D, Kaminski N, Tzouvelekis A. Karampitsakos T, et al. Diagnostics (Basel). 2023 Mar 18;13(6):1166. doi: 10.3390/diagnostics13061166. Diagnostics (Basel). 2023. PMID: 36980473 Free PMC article.
New horizons in human sperm selection for assisted reproduction.
Nixon B, Schjenken JE, Burke ND, Skerrett-Byrne DA, Hart HM, De Iuliis GN, Martin JH, Lord T, Bromfield EG. Nixon B, et al. Among authors: de iuliis gn. Front Endocrinol (Lausanne). 2023 Feb 22;14:1145533. doi: 10.3389/fendo.2023.1145533. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36909306 Free PMC article. Review.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.
Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. Ahangari F, et al. JCI Insight. 2023 Feb 22;8(4):e158100. doi: 10.1172/jci.insight.158100. JCI Insight. 2023. PMID: 36626225 Free PMC article.
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia.
Bernard-Raichon L, Venzon M, Klein J, Axelrad JE, Zhang C, Sullivan AP, Hussey GA, Casanovas-Massana A, Noval MG, Valero-Jimenez AM, Gago J, Putzel G, Pironti A, Wilder E; Yale IMPACT Research Team; Thorpe LE, Littman DR, Dittmann M, Stapleford KA, Shopsin B, Torres VJ, Ko AI, Iwasaki A, Cadwell K, Schluter J. Bernard-Raichon L, et al. Nat Commun. 2022 Nov 1;13(1):5926. doi: 10.1038/s41467-022-33395-6. Nat Commun. 2022. PMID: 36319618 Free PMC article.
93 results