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TDP-43: A Key Therapeutic Target beyond Amyotrophic Lateral Sclerosis.
Palomo V, Tosat-Bitrian C, Nozal V, Nagaraj S, Martin-Requero A, Martinez A. Palomo V, et al. Among authors: martinez a. ACS Chem Neurosci. 2019 Mar 20;10(3):1183-1196. doi: 10.1021/acschemneuro.9b00026. Epub 2019 Mar 4. ACS Chem Neurosci. 2019. PMID: 30785719 Free article. Review.
Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á. Vaca G, et al. Among authors: martinez gonzalez l, martinez a. J Neurochem. 2021 Feb;156(3):379-390. doi: 10.1111/jnc.15118. Epub 2020 Jul 17. J Neurochem. 2021. PMID: 32628315 Free article.
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis.
Rojas-Prats E, Martinez-Gonzalez L, Gonzalo-Consuegra C, Liachko NF, Perez C, Ramírez D, Kraemer BC, Martin-Requero Á, Perez DI, Gil C, de Lago E, Martinez A. Rojas-Prats E, et al. Among authors: martinez gonzalez l, martinez a. Eur J Med Chem. 2021 Jan 15;210:112968. doi: 10.1016/j.ejmech.2020.112968. Epub 2020 Oct 28. Eur J Med Chem. 2021. PMID: 33139113
From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein-Templated Synthesis.
Nozal V, García-Rubia A, Cuevas EP, Pérez C, Tosat-Bitrián C, Bartolomé F, Carro E, Ramírez D, Palomo V, Martínez A. Nozal V, et al. Among authors: martinez a. Angew Chem Int Ed Engl. 2021 Aug 23;60(35):19344-19354. doi: 10.1002/anie.202106295. Epub 2021 Jul 26. Angew Chem Int Ed Engl. 2021. PMID: 34169618 Free PMC article.
8,510 results