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Blocking cholesterol storage to treat Alzheimer's disease.
Chang TY, Chang CCY, Harned TC, De La Torre AL, Lee J, Huynh TN, Gow JG. Chang TY, et al. Among authors: harned tc. Explor Neuroprotective Ther. 2021 Dec 30;1(3):173-184. doi: 10.37349/ent.2021.00014. Explor Neuroprotective Ther. 2021. PMID: 35199105 Free PMC article.
Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester biosynthesis without overt toxicity in neuronal cell culture.
De La Torre AL, Smith C, Granger J, Anderson FL, Harned TC, Havrda MC, Chang CCY, Chang TY. De La Torre AL, et al. Among authors: harned tc. J Neurosci Methods. 2022 Feb 1;367:109437. doi: 10.1016/j.jneumeth.2021.109437. Epub 2021 Dec 7. J Neurosci Methods. 2022. PMID: 34890698 Free PMC article.