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Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.
Janssen B, Tian G, Lengyel-Zhand Z, Hsieh CJ, Lougee MG, Riad A, Xu K, Hou C, Weng CC, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH. Janssen B, et al. Among authors: lengyel zhand z. Mol Imaging Biol. 2023 Aug;25(4):704-719. doi: 10.1007/s11307-023-01814-9. Epub 2023 Mar 29. Mol Imaging Biol. 2023. PMID: 36991273 Free PMC article.
Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples.
Puentes LN, Lengyel-Zhand Z, Lee JY, Hsieh CJ, Schneider ME Jr, Edwards KJ, Luk KC, Lee VM, Trojanowski JQ, Mach RH. Puentes LN, et al. Among authors: lengyel zhand z. Front Aging Neurosci. 2021 Jun 18;13:704041. doi: 10.3389/fnagi.2021.704041. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34220490 Free PMC article.
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.
Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. Kim HY, et al. Among authors: lengyel zhand z. J Med Chem. 2023 Sep 14;66(17):12185-12202. doi: 10.1021/acs.jmedchem.3c00779. Epub 2023 Aug 31. J Med Chem. 2023. PMID: 37651366 Free PMC article.
Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model.
Garnsey MR, Robinson MC, Nguyen LT, Cardin R, Tillotson J, Mashalidis E, Yu A, Aschenbrenner L, Balesano A, Behzadi A, Boras B, Chang JS, Eng H, Ephron A, Foley T, Ford KK, Frick JM, Gibson S, Hao L, Hurst B, Kalgutkar AS, Korczynska M, Lengyel-Zhand Z, Gao L, Meredith HR, Patel NC, Polivkova J, Rai D, Rose CR, Rothan H, Sakata SK, Vargo TR, Qi W, Wu H, Liu Y, Yurgelonis I, Zhang J, Zhu Y, Zhang L, Lee AA. Garnsey MR, et al. Among authors: lengyel zhand z. Sci Adv. 2024 Aug 30;10(35):eado4288. doi: 10.1126/sciadv.ado4288. Epub 2024 Aug 30. Sci Adv. 2024. PMID: 39213347 Free PMC article.
14 results