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Transcriptome analysis of primary adult B-cell lineage acute lymphoblastic leukemia identifies pathogenic variants and gene fusions, and predicts subtypes for in depth molecular diagnosis.
Podgorica M, Drivet E, Viken JK, Richman A, Vestbøstad J, Szodoray P, Kvam AK, Wik HS, Tjønnfjord GE, Munthe LA, Frietze S, Schjerven H. Podgorica M, et al. Among authors: schjerven h. Eur J Haematol. 2024 May;112(5):731-742. doi: 10.1111/ejh.14164. Epub 2024 Jan 8. Eur J Haematol. 2024. PMID: 38192186
Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance.
Sin JH, Sucharov J, Kashyap S, Wang Y, Proekt I, Liu X, Parent AV, Gupta A, Kastner P, Chan S, Gardner JM, Ntranos V, Miller CN, Anderson MS, Schjerven H, Waterfield MR. Sin JH, et al. Among authors: schjerven h. Sci Immunol. 2023 Oct 27;8(88):eabq3109. doi: 10.1126/sciimmunol.abq3109. Epub 2023 Oct 27. Sci Immunol. 2023. PMID: 37889983 Free PMC article.
Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies.
Cosgun KN, Jumaa H, Robinson ME, Kistner KM, Xu L, Xiao G, Chan LN, Lee J, Kume K, Leveille E, Fonseca-Arce D, Khanduja D, Ng HL, Feldhahn N, Song J, Chan WC, Chen J, Taketo MM, Kothari S, Davids MS, Schjerven H, Jellusova J, Müschen M. Cosgun KN, et al. Among authors: schjerven h. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532152. doi: 10.1101/2023.03.13.532152. bioRxiv. 2023. PMID: 36993619 Free PMC article. Preprint.
Ikaros Regulates microRNA Networks in Acute Lymphoblastic Leukemia.
Kogut S, Paculova H, Rodriguez P, Boyd J, Richman A, Palaria A, Schjerven H, Frietze S. Kogut S, et al. Among authors: schjerven h. Epigenomes. 2022 Oct 19;6(4):37. doi: 10.3390/epigenomes6040037. Epigenomes. 2022. PMID: 36278683 Free PMC article.
Non-Coding RNA Signatures of B-Cell Acute Lymphoblastic Leukemia.
Rodriguez PD, Paculova H, Kogut S, Heath J, Schjerven H, Frietze S. Rodriguez PD, et al. Among authors: schjerven h. Int J Mol Sci. 2021 Mar 7;22(5):2683. doi: 10.3390/ijms22052683. Int J Mol Sci. 2021. PMID: 33799946 Free PMC article. Review.
Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.
Park E, Chen J, Moore A, Mangolini M, Santoro A, Boyd JR, Schjerven H, Ecker V, Buchner M, Williamson JC, Lehner PJ, Gasparoli L, Williams O, Bloehdorn J, Stilgenbauer S, Leitges M, Egle A, Schmidt-Supprian M, Frietze S, Ringshausen I. Park E, et al. Among authors: schjerven h. Sci Transl Med. 2020 Jan 15;12(526):eaax9340. doi: 10.1126/scitranslmed.aax9340. Sci Transl Med. 2020. PMID: 31941829 Free PMC article.
Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors.
Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M. Chan LN, et al. Among authors: schjerven h. Nature. 2018 Jun;558(7711):E5. doi: 10.1038/s41586-018-0164-5. Nature. 2018. PMID: 29849140
A kindred with mutant IKAROS and autoimmunity.
Van Nieuwenhove E, Garcia-Perez JE, Helsen C, Rodriguez PD, van Schouwenburg PA, Dooley J, Schlenner S, van der Burg M, Verhoeyen E, Gijsbers R, Frietze S, Schjerven H, Meyts I, Claessens F, Humblet-Baron S, Wouters C, Liston A. Van Nieuwenhove E, et al. Among authors: schjerven h. J Allergy Clin Immunol. 2018 Aug;142(2):699-702.e12. doi: 10.1016/j.jaci.2018.04.008. Epub 2018 Apr 27. J Allergy Clin Immunol. 2018. PMID: 29705243 Free PMC article.
30 results