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Page 1
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D; CommonMind Consortium; Akbarian S, Roussos P, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK. Dobbyn A, et al. Among authors: hoffman ge. Am J Hum Genet. 2018 Jun 7;102(6):1169-1184. doi: 10.1016/j.ajhg.2018.04.011. Epub 2018 May 24. Am J Hum Genet. 2018. PMID: 29805045 Free PMC article.
Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data.
Dai R, Chu T, Zhang M, Wang X, Jourdon A, Wu F, Mariani J, Vaccarino FM, Lee D, Fullard JF, Hoffman GE, Roussos P, Wang Y, Wang X, Pinto D, Wang SH, Zhang C; PsychENCODE consortium; Chen C, Liu C. Dai R, et al. Among authors: hoffman ge. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532468. doi: 10.1101/2023.03.13.532468. bioRxiv. 2023. Update in: Sci Adv. 2024 May 24;10(21):eadh2588. doi: 10.1126/sciadv.adh2588 PMID: 36993743 Free PMC article. Updated. Preprint.
Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases.
Zeng B, Bendl J, Deng C, Lee D, Misir R, Reach SM, Kleopoulos SP, Auluck P, Marenco S, Lewis DA, Haroutunian V, Ahituv N, Fullard JF, Hoffman GE, Roussos P. Zeng B, et al. Among authors: hoffman ge. bioRxiv [Preprint]. 2023 Mar 2:2023.03.02.530826. doi: 10.1101/2023.03.02.530826. bioRxiv. 2023. Update in: Science. 2024 May 24;384(6698):eadh4265. doi: 10.1126/science.adh4265 PMID: 37090548 Free PMC article. Updated. Preprint.
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
Girdhar K, Bendl J, Baumgartner A, Therrien K, Venkatesh S, Mathur D, Dong P, Rahman S, Kleopoulos SP, Misir R, Reach SM, Auluck PK, Marenco S, Lewis DA, Haroutunian V, Funk C, Voloudakis G, Hoffman GE, Fullard JF, Roussos P. Girdhar K, et al. Among authors: hoffman ge. medRxiv [Preprint]. 2023 Oct 3:2023.10.02.23296067. doi: 10.1101/2023.10.02.23296067. medRxiv. 2023. PMID: 37873320 Free PMC article. Preprint.
A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex.
Huuki-Myers LA, Spangler A, Eagles NJ, Montgomery KD, Kwon SH, Guo B, Grant-Peters M, Divecha HR, Tippani M, Sriworarat C, Nguyen AB, Ravichandran P, Tran MN, Seyedian A; PsychENCODE Consortium†; Hyde TM, Kleinman JE, Battle A, Page SC, Ryten M, Hicks SC, Martinowich K, Collado-Torres L, Maynard KR; PsychENCODE Consortium. Huuki-Myers LA, et al. Science. 2024 May 24;384(6698):eadh1938. doi: 10.1126/science.adh1938. Epub 2024 May 24. Science. 2024. PMID: 38781370 Free PMC article.
Massively parallel characterization of regulatory elements in the developing human cortex.
Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM; PsychENCODE Consortium‡; Pollen AA, Nowakowski TJ, Ahituv N, Pollard KS; PsychENCODE Consortium. Deng C, et al. Science. 2024 May 24;384(6698):eadh0559. doi: 10.1126/science.adh0559. Epub 2024 May 24. Science. 2024. PMID: 38781390
Biological Insights from Schizophrenia-associated Loci in Ancestral Populations.
Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Rajeevan N, Sayward F, Cheung KH; Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS); Consortium on the Genomics of Schizophrenia (COGS); Genomic Psychiatry Cohort (GPC) Investigators; DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley P, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN; PsychAD Consortium; Cooperative Studies Program (CSP) #572; Million Veteran Program (MVP); Huang GD, Muralidhar S, Michael Gaziano J, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. Bigdeli TB, et al. Among authors: hoffman ge. medRxiv [Preprint]. 2024 Aug 28:2024.08.27.24312631. doi: 10.1101/2024.08.27.24312631. medRxiv. 2024. PMID: 39252912 Free PMC article. Preprint.
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder.
Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, Moran Losada P, Khan Z, Mleczko J, Xia Y, Dai R, Wang D, Yang YT, Xu M, Fish K, Hof PR, Warrell J, Fitzgerald D, White K, Jaffe AE; PsychENCODE Consortium; Peters MA, Gerstein M, Liu C, Iakoucheva LM, Pinto D, Geschwind DH. Gandal MJ, et al. Science. 2018 Dec 14;362(6420):eaat8127. doi: 10.1126/science.aat8127. Science. 2018. PMID: 30545856 Free PMC article.
232 results