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Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors.
Schauer NJ, Magin RS, Liu X, Doherty LM, Buhrlage SJ. Schauer NJ, et al. Among authors: buhrlage sj. J Med Chem. 2020 Mar 26;63(6):2731-2750. doi: 10.1021/acs.jmedchem.9b01138. Epub 2019 Nov 20. J Med Chem. 2020. PMID: 31682427 Review.
Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors.
Bushman JW, Donovan KA, Schauer NJ, Liu X, Hu W, Varca AC, Buhrlage SJ, Fischer ES. Bushman JW, et al. Among authors: buhrlage sj. Cell Chem Biol. 2021 Jan 21;28(1):78-87.e3. doi: 10.1016/j.chembiol.2020.09.005. Epub 2020 Oct 1. Cell Chem Biol. 2021. PMID: 33007217 Free PMC article.
Identification and validation of selective deubiquitinase inhibitors.
Varca AC, Casalena D, Chan WC, Hu B, Magin RS, Roberts RM, Liu X, Zhu H, Seo HS, Dhe-Paganon S, Marto JA, Auld D, Buhrlage SJ. Varca AC, et al. Among authors: buhrlage sj. Cell Chem Biol. 2021 Dec 16;28(12):1758-1771.e13. doi: 10.1016/j.chembiol.2021.05.012. Epub 2021 Jun 14. Cell Chem Biol. 2021. PMID: 34129829 Free PMC article.
Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Lamberto I, Liu X, Seo HS, Schauer NJ, Iacob RE, Hu W, Das D, Mikhailova T, Weisberg EL, Engen JR, Anderson KC, Chauhan D, Dhe-Paganon S, Buhrlage SJ. Lamberto I, et al. Among authors: buhrlage sj. Cell Chem Biol. 2017 Dec 21;24(12):1490-1500.e11. doi: 10.1016/j.chembiol.2017.09.003. Epub 2017 Oct 19. Cell Chem Biol. 2017. PMID: 29056421 Free PMC article.
66 results