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Page 1
Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade.
Pai JA, Hellmann MD, Sauter JL, Mattar M, Rizvi H, Woo HJ, Shah N, Nguyen EM, Uddin FZ, Quintanal-Villalonga A, Chan JM, Manoj P, Allaj V, Baine MK, Bhanot UK, Jain M, Linkov I, Meng F, Brown D, Chaft JE, Plodkowski AJ, Gigoux M, Won HH, Sen T, Wells DK, Donoghue MTA, de Stanchina E, Wolchok JD, Loomis B, Merghoub T, Rudin CM, Chow A, Satpathy AT. Pai JA, et al. Among authors: satpathy at. Cancer Cell. 2023 Apr 10;41(4):776-790.e7. doi: 10.1016/j.ccell.2023.03.009. Epub 2023 Mar 30. Cancer Cell. 2023. PMID: 37001526 Free PMC article.
Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion.
Cohen Shvefel S, Pai JA, Cao Y, Pal LR, Levy R, Yao W, Cheng K, Zemanek M, Bartok O, Weller C, Yin Y, Du PP, Yakubovich E, Orr I, Ben-Dor S, Oren R, Fellus-Alyagor L, Golani O, Goliand I, Ranmar D, Savchenko I, Ketrarou N, Schäffer AA, Ruppin E, Satpathy AT, Samuels Y. Cohen Shvefel S, et al. Among authors: satpathy at. bioRxiv [Preprint]. 2023 Nov 29:2023.11.29.569032. doi: 10.1101/2023.11.29.569032. bioRxiv. 2023. PMID: 38077050 Free PMC article. Preprint.
Inosine induces stemness features in CAR-T cells and enhances potency.
Klysz DD, Fowler C, Malipatlolla M, Stuani L, Freitas KA, Chen Y, Meier S, Daniel B, Sandor K, Xu P, Huang J, Labanieh L, Keerthi V, Leruste A, Bashti M, Mata-Alcazar J, Gkitsas N, Guerrero JA, Fisher C, Patel S, Asano K, Patel S, Davis KL, Satpathy AT, Feldman SA, Sotillo E, Mackall CL. Klysz DD, et al. Among authors: satpathy at. Cancer Cell. 2024 Feb 12;42(2):266-282.e8. doi: 10.1016/j.ccell.2024.01.002. Epub 2024 Jan 25. Cancer Cell. 2024. PMID: 38278150 Free article.
Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders.
Toh J, Reitsma AJ, Tajima T, Younes SF, Ezeiruaku C, Jenkins KC, Peña JK, Zhao S, Wang X, Lee EYZ, Glass MC, Kalesinskas L, Ganesan A, Liang I, Pai JA, Harden JT, Vallania F, Vizcarra EA, Bhagat G, Craig FE, Swerdlow SH, Morscio J, Dierickx D, Tousseyn T, Satpathy AT, Krams SM, Natkunam Y, Khatri P, Martinez OM. Toh J, et al. Among authors: satpathy at. Cell Rep Med. 2024 Dec 17;5(12):101851. doi: 10.1016/j.xcrm.2024.101851. Epub 2024 Dec 9. Cell Rep Med. 2024. PMID: 39657667 Free article.
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.
Tsuchida CA, Brandes N, Bueno R, Trinidad M, Mazumder T, Yu B, Hwang B, Chang C, Liu J, Sun Y, Hopkins CR, Parker KR, Qi Y, Hofman L, Satpathy AT, Stadtmauer EA, Cate JHD, Eyquem J, Fraietta JA, June CH, Chang HY, Ye CJ, Doudna JA. Tsuchida CA, et al. Among authors: satpathy at. Cell. 2023 Oct 12;186(21):4567-4582.e20. doi: 10.1016/j.cell.2023.08.041. Epub 2023 Oct 3. Cell. 2023. PMID: 37794590 Free PMC article.
Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state.
Daniel B, Belk JA, Meier SL, Chen AY, Sandor K, Czimmerer Z, Varga Z, Bene K, Buquicchio FA, Qi Y, Kitano H, Wheeler JR, Foster DS, Januszyk M, Longaker MT, Chang HY, Satpathy AT. Daniel B, et al. Among authors: satpathy at. Mol Cell. 2023 Jan 5;83(1):121-138.e7. doi: 10.1016/j.molcel.2022.11.017. Epub 2022 Dec 14. Mol Cell. 2023. PMID: 36521490 Free PMC article.
Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation.
Buquicchio FA, Fonseca R, Yan PK, Wang F, Evrard M, Obers A, Gutierrez JC, Raposo CJ, Belk JA, Daniel B, Zareie P, Yost KE, Qi Y, Yin Y, Nico KF, Tierney FM, Howitt MR, Lareau CA, Satpathy AT, Mackay LK. Buquicchio FA, et al. Among authors: satpathy at. Immunity. 2024 Sep 10;57(9):2202-2215.e6. doi: 10.1016/j.immuni.2024.06.014. Epub 2024 Jul 22. Immunity. 2024. PMID: 39043184
Engineered cell entry links receptor biology with single-cell genomics.
Yu B, Shi Q, Belk JA, Yost KE, Parker KR, Li R, Liu BB, Huang H, Lingwood D, Greenleaf WJ, Davis MM, Satpathy AT, Chang HY. Yu B, et al. Among authors: satpathy at. Cell. 2022 Dec 22;185(26):4904-4920.e22. doi: 10.1016/j.cell.2022.11.016. Epub 2022 Dec 13. Cell. 2022. PMID: 36516854 Free PMC article.
Inosine Induces Stemness Features in CAR T cells and Enhances Potency.
Klysz DD, Fowler C, Malipatlolla M, Stuani L, Freitas KA, Meier S, Daniel B, Sandor K, Xu P, Huang J, Labanieh L, Leruste A, Bashti M, Keerthi V, Mata-Alcazar J, Gkitsas N, Guerrero JA, Fisher C, Patel S, Asano K, Patel S, Davis KL, Satpathy AT, Feldman SA, Sotillo E, Mackall CL. Klysz DD, et al. Among authors: satpathy at. bioRxiv [Preprint]. 2023 Apr 25:2023.04.21.537859. doi: 10.1101/2023.04.21.537859. bioRxiv. 2023. Update in: Cancer Cell. 2024 Feb 12;42(2):266-282.e8. doi: 10.1016/j.ccell.2024.01.002 PMID: 37162847 Free PMC article. Updated. Preprint.
138 results