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Page 1
Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization.
Izadi A, Hailu A, Godzwon M, Wrighton S, Olofsson B, Schmidt T, Söderlund-Strand A, Elder E, Appelberg S, Valsjö M, Larsson O, Wendel-Hansen V, Ohlin M, Bahnan W, Nordenfelt P. Izadi A, et al. Among authors: godzwon m. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2217590120. doi: 10.1073/pnas.2217590120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011197 Free PMC article.
Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2.
Bahnan W, Wrighton S, Sundwall M, Bläckberg A, Larsson O, Höglund U, Khakzad H, Godzwon M, Walle M, Elder E, Strand AS, Happonen L, André O, Ahnlide JK, Hellmark T, Wendel-Hansen V, Wallin RP, Malmstöm J, Malmström L, Ohlin M, Rasmussen M, Nordenfelt P. Bahnan W, et al. Among authors: godzwon m. Front Immunol. 2022 Jan 14;12:808932. doi: 10.3389/fimmu.2021.808932. eCollection 2021. Front Immunol. 2022. PMID: 35095897 Free PMC article.
The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies.
Izadi A, Karami Y, Bratanis E, Wrighton S, Khakzad H, Nyblom M, Olofsson B, Happonen L, Tang D, Sundwall M, Godzwon M, Chao Y, Toledo AG, Schmidt T, Ohlin M, Nilges M, Malmström J, Bahnan W, Shannon O, Malmström L, Nordenfelt P. Izadi A, et al. Among authors: godzwon m. Nat Commun. 2024 Apr 27;15(1):3600. doi: 10.1038/s41467-024-47928-8. Nat Commun. 2024. PMID: 38678029 Free PMC article.
Protective Non-neutralizing anti-N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated Virulence.
Izadi A, Godzwon M, Söderlund Strand A, Schmidt T, Kumlien Georén S, Drosten C, Ohlin M, Nordenfelt P. Izadi A, et al. Among authors: godzwon m. J Immunol. 2024 Sep 1;213(5):678-689. doi: 10.4049/jimmunol.2300675. J Immunol. 2024. PMID: 39018495 Free PMC article.
A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
Glesner J, Kapingidza AB, Godzwon M, Offermann LR, Mueller GA, DeRose EF, Wright P, Richardson CM, Woodfolk JA, Vailes LD, Wünschmann S, London RE, Chapman MD, Ohlin M, Chruszcz M, Pomés A. Glesner J, et al. Among authors: godzwon m. J Immunol. 2019 Nov 1;203(9):2545-2556. doi: 10.4049/jimmunol.1900580. Epub 2019 Sep 25. J Immunol. 2019. PMID: 31554696 Free PMC article.