Couto M - Search Results

1

A Potential Boron Neutron Capture Therapy Agent Selectively Suppresses High-Grade Glioma: In Vitro and in Vivo Exploration.

Alamón C, Dávila B, García MF, Nievas S, Dagrosa MA, Thorp S, Kovacs M, Trias E, Faccio R, Gabay M, Zeineh N, Weizman A, Teixidor F, Viñas C, Gavish M, Cerecetto H, Couto M. Alamón C, et al. Among authors: couto m. Mol Pharm. 2023 May 1;20(5):2702-2713. doi: 10.1021/acs.molpharmaceut.3c00152. Epub 2023 Apr 4. Mol Pharm. 2023. PMID: 37013916

2

A serendipitous one-step conversion of 3H-1,2-dithiole-3-thione to (E)-3-[1-(alkylthio)alkylidene]-3H-1,2-dithiole: an experimental and theoretical study.

Couto M, Cabrera M, Echeverría GA, Piro OE, González M, Cerecetto H. Couto M, et al. Mol Divers. 2014 May;18(2):285-94. doi: 10.1007/s11030-013-9499-x. Epub 2014 Jan 14. Mol Divers. 2014. PMID: 24420794

3

Searching phase II enzymes inducers, from Michael acceptor-[1,2]dithiolethione hybrids, as cancer chemopreventive agents.

Couto M, de Ovalle S, Cabrera M, Cerecetto H, González M. Couto M, et al. Future Med Chem. 2015;7(7):857-71. doi: 10.4155/fmc.15.32. Future Med Chem. 2015. PMID: 26061105

4

3-H-[1,2]Dithiole as a New Anti-Trypanosoma cruzi Chemotype: Biological and Mechanism of Action Studies.

Couto M, Sánchez C, Dávila B, Machín V, Varela J, Álvarez G, Cabrera M, Celano L, Aguirre-López B, Cabrera N, de Gómez-Puyou MT, Gómez-Puyou A, Pérez-Montfort R, Cerecetto H, González M. Couto M, et al. Molecules. 2015 Aug 12;20(8):14595-610. doi: 10.3390/molecules200814595. Molecules. 2015. PMID: 26274947 Free PMC article.

5

Small-Molecule Kinase-Inhibitors-Loaded Boron Cluster as Hybrid Agents for Glioma-Cell-Targeting Therapy.

Couto M, Mastandrea I, Cabrera M, Cabral P, Teixidor F, Cerecetto H, Viñas C. Couto M, et al. Chemistry. 2017 Jul 12;23(39):9233-9238. doi: 10.1002/chem.201701965. Epub 2017 Jul 3. Chemistry. 2017. PMID: 28605114

6

Discovery of Potent EGFR Inhibitors through the Incorporation of a 3D-Aromatic-Boron-Rich-Cluster into the 4-Anilinoquinazoline Scaffold: Potential Drugs for Glioma Treatment.

Couto M, García MF, Alamón C, Cabrera M, Cabral P, Merlino A, Teixidor F, Cerecetto H, Viñas C. Couto M, et al. Chemistry. 2018 Mar 2;24(13):3122-3126. doi: 10.1002/chem.201705181. Epub 2017 Dec 22. Chemistry. 2018. PMID: 29194843

7

Synthesis of hydrophilic HYNIC-[1,2,4,5]tetrazine conjugates and their use in antibody pretargeting with ^99mTc.

García MF, Gallazzi F, Junqueira MS, Fernández M, Camacho X, Mororó JDS, Faria D, Carneiro CG, Couto M, Carrión F, Pritsch O, Chammas R, Quinn T, Cabral P, Cerecetto H. García MF, et al. Among authors: couto m. Org Biomol Chem. 2018 Jul 25;16(29):5275-5285. doi: 10.1039/c8ob01255e. Org Biomol Chem. 2018. PMID: 29974915

8

Carboranylanilinoquinazoline EGFR-inhibitors: toward 'lead-to-candidate' stage in the drug-development pipeline.

Couto M, Alamón C, Sánchez C, Dávila B, Fernández M, Lecot N, Cabral P, Teixidor F, Viñas C, Cerecetto H. Couto M, et al. Future Med Chem. 2019 Sep;11(17):2273-2285. doi: 10.4155/fmc-2019-0060. Future Med Chem. 2019. PMID: 31581913

9

Closo-Carboranyl- and Metallacarboranyl [1,2,3]triazolyl-Decorated Lapatinib-Scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy.

Couto M, Alamón C, García MF, Kovacs M, Trias E, Nievas S, Pozzi E, Curotto P, Thorp S, Dagrosa MA, Teixidor F, Viñas C, Cerecetto H. Couto M, et al. Cells. 2020 Jun 5;9(6):1408. doi: 10.3390/cells9061408. Cells. 2020. PMID: 32517054 Free PMC article.

10

Bimodal Therapeutic Agents Against Glioblastoma, One of the Most Lethal Forms of Cancer.

Couto M, Alamón C, Nievas S, Perona M, Dagrosa MA, Teixidor F, Cabral P, Viñas C, Cerecetto H. Couto M, et al. Chemistry. 2020 Nov 11;26(63):14335-14340. doi: 10.1002/chem.202002963. Epub 2020 Oct 6. Chemistry. 2020. PMID: 32738078

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