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Targeting mitochondrial energetics reverses panobinostat- and marizomib-induced resistance in pediatric and adult high-grade gliomas.
Jane EP, Reslink MC, Gatesman TA, Halbert ME, Miller TA, Golbourn BJ, Casillo SM, Mullett SJ, Wendell SG, Obodo U, Mohanakrishnan D, Dange R, Michealraj A, Brenner C, Agnihotri S, Premkumar DR, Pollack IF. Jane EP, et al. Among authors: mullett sj. Mol Oncol. 2023 Sep;17(9):1821-1843. doi: 10.1002/1878-0261.13427. Epub 2023 May 12. Mol Oncol. 2023. PMID: 37014128 Free PMC article.
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.
Li J, Garavaglia S, Ye Z, Moretti A, Belyaeva OV, Beiser A, Ibrahim M, Wilk A, McClellan S, Klyuyeva AV, Goggans KR, Kedishvili NY, Salter EA, Wierzbicki A, Migaud ME, Mullett SJ, Yates NA, Camacho CJ, Rizzi M, Sobol RW. Li J, et al. Among authors: mullett sj. Commun Biol. 2021 Dec 21;4(1):1420. doi: 10.1038/s42003-021-02949-7. Commun Biol. 2021. PMID: 34934174 Free PMC article.
BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.
Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J 3rd, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY. Yu Q, et al. Among authors: mullett sj. Circulation. 2019 May 7;139(19):2238-2255. doi: 10.1161/CIRCULATIONAHA.118.035889. Circulation. 2019. PMID: 30759996 Free PMC article.
Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice.
Thapa D, Xie B, Zhang M, Stoner MW, Manning JR, Huckestein BR, Edmunds LR, Mullett SJ, McTiernan CF, Wendell SG, Jurczak MJ, Scott I. Thapa D, et al. Among authors: mullett sj. J Mol Cell Cardiol. 2019 Apr;129:174-178. doi: 10.1016/j.yjmcc.2019.02.012. Epub 2019 Feb 26. J Mol Cell Cardiol. 2019. PMID: 30822408 Free PMC article.
Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.
Weisel FJ, Mullett SJ, Elsner RA, Menk AV, Trivedi N, Luo W, Wikenheiser D, Hawse WF, Chikina M, Smita S, Conter LJ, Joachim SM, Wendell SG, Jurczak MJ, Winkler TH, Delgoffe GM, Shlomchik MJ. Weisel FJ, et al. Among authors: mullett sj. Nat Immunol. 2020 Mar;21(3):331-342. doi: 10.1038/s41590-020-0598-4. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066950 Free PMC article.
Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses.
Houston R, Sekine S, Calderon MJ, Seifuddin F, Wang G, Kawagishi H, Malide DA, Li Y, Gucek M, Pirooznia M, Nelson AJ, Stokes MP, Stewart-Ornstein J, Mullett SJ, Wendell SG, Watkins SC, Finkel T, Sekine Y. Houston R, et al. Among authors: mullett sj. PLoS Biol. 2020 Nov 30;18(11):e3000981. doi: 10.1371/journal.pbio.3000981. eCollection 2020 Nov. PLoS Biol. 2020. PMID: 33253182 Free PMC article.
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.
Watson MJ, Vignali PDA, Mullett SJ, Overacre-Delgoffe AE, Peralta RM, Grebinoski S, Menk AV, Rittenhouse NL, DePeaux K, Whetstone RD, Vignali DAA, Hand TW, Poholek AC, Morrison BM, Rothstein JD, Wendell SG, Delgoffe GM. Watson MJ, et al. Among authors: mullett sj. Nature. 2021 Mar;591(7851):645-651. doi: 10.1038/s41586-020-03045-2. Epub 2021 Feb 15. Nature. 2021. PMID: 33589820 Free PMC article.
Sustained Dysbiosis and Decreased Fecal Short-Chain Fatty Acids after Traumatic Brain Injury and Impact on Neurologic Outcome.
Opeyemi OM, Rogers MB, Firek BA, Janesko-Feldman K, Vagni V, Mullett SJ, Wendell SG, Nelson BP, New LA, Mariño E, Kochanek PM, Bayır H, Clark RSB, Morowitz MJ, Simon DW. Opeyemi OM, et al. Among authors: mullett sj. J Neurotrauma. 2021 Sep 15;38(18):2610-2621. doi: 10.1089/neu.2020.7506. Epub 2021 Jun 7. J Neurotrauma. 2021. PMID: 33957773 Free PMC article.
42 results