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Dual Molecules Targeting 5-HT6 and GABA-A Receptors as a New Approach to Combat Depression Associated with Neuroinflammation.
Marcinkowska M, Mordyl B, Siwek A, Głuch-Lutwin M, Karcz T, Gawalska A, Sapa M, Bucki A, Szafrańska K, Pomierny B, Pytka K, Kotańska M, Mika K, Kolaczkowski M. Marcinkowska M, et al. Among authors: karcz t. ACS Chem Neurosci. 2023 Apr 4;14(8):1474-89. doi: 10.1021/acschemneuro.3c00033. Online ahead of print. ACS Chem Neurosci. 2023. PMID: 37014731 Free PMC article.
Novel Piperazine Arylideneimidazolones Inhibit the AcrAB-TolC Pump in Escherichia coli and Simultaneously Act as Fluorescent Membrane Probes in a Combined Real-Time Influx and Efflux Assay.
Bohnert JA, Schuster S, Kern WV, Karcz T, Olejarz A, Kaczor A, Handzlik J, Kieć-Kononowicz K. Bohnert JA, et al. Among authors: karcz t. Antimicrob Agents Chemother. 2016 Mar 25;60(4):1974-83. doi: 10.1128/AAC.01995-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26824939 Free PMC article.
Design, synthesis, and biological evaluation of fluorinated imidazo[1,2-a]pyridine derivatives with potential antipsychotic activity.
Marcinkowska M, Kołaczkowski M, Kamiński K, Bucki A, Pawłowski M, Siwek A, Karcz T, Mordyl B, Starowicz G, Kubowicz P, Pękala E, Wesołowska A, Samochowiec J, Mierzejewski P, Bienkowski P. Marcinkowska M, et al. Among authors: karcz t. Eur J Med Chem. 2016 Nov 29;124:456-467. doi: 10.1016/j.ejmech.2016.08.059. Epub 2016 Aug 26. Eur J Med Chem. 2016. PMID: 27598234
3-Aminomethyl Derivatives of 2-Phenylimidazo[1,2-a]-pyridine as Positive Allosteric Modulators of GABAA Receptor with Potential Antipsychotic Activity.
Marcinkowska M, Kołaczkowski M, Kamiński K, Bucki A, Pawłowski M, Siwek A, Karcz T, Starowicz G, Słoczyńska K, Pękala E, Wesołowska A, Samochowiec J, Mierzejewski P, Bienkowski P. Marcinkowska M, et al. Among authors: karcz t. ACS Chem Neurosci. 2017 Jun 21;8(6):1291-1298. doi: 10.1021/acschemneuro.6b00432. Epub 2017 Mar 1. ACS Chem Neurosci. 2017. PMID: 28211669
Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate.
Kaproń B, Łuszczki J, Paneth A, Wujec M, Siwek A, Karcz T, Mordyl B, Głuch-Lutwin M, Gryboś A, Nowak G, Pająk K, Jóźwiak K, Tomczykowski A, Plech T. Kaproń B, et al. Among authors: karcz t. Int J Med Sci. 2017 Jul 18;14(8):741-749. doi: 10.7150/ijms.20001. eCollection 2017. Int J Med Sci. 2017. PMID: 28824309 Free PMC article.
59 results