Breuil L - Search Results

1

The Risk of P-Glycoprotein-Mediated Drug-Drug Interaction May Also Depend on The Vulnerability of The Victim Substrate to Partial Inhibition.

Breuil L, Marie S, Tournier N. Breuil L, et al. J Pharm Sci. 2023 Jul;112(7):2005. doi: 10.1016/j.xphs.2023.03.023. Epub 2023 Apr 4. J Pharm Sci. 2023. PMID: 37023854 No abstract available.

2

Validation of Pharmacological Protocols for Targeted Inhibition of Canalicular MRP2 Activity in Hepatocytes Using [^99mTc]mebrofenin Imaging in Rats.

Marie S, Hernández-Lozano I, Breuil L, Saba W, Novell A, Gennisson JL, Langer O, Truillet C, Tournier N. Marie S, et al. Among authors: breuil l. Pharmaceutics. 2020 May 27;12(6):486. doi: 10.3390/pharmaceutics12060486. Pharmaceutics. 2020. PMID: 32471244 Free PMC article.

3

An original radio-biomimetic approach to synthesize radiometabolites for PET imaging.

Auvity S, Breuil L, Goislard M, Bottlaender M, Kuhnast B, Tournier N, Caillé F. Auvity S, et al. Among authors: breuil l. Nucl Med Biol. 2020 Nov-Dec;90-91:10-14. doi: 10.1016/j.nucmedbio.2020.08.001. Epub 2020 Aug 23. Nucl Med Biol. 2020. PMID: 32898790

4

Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [¹¹C]erlotinib.

Tournier N, Goutal S, Mairinger S, Hernández-Lozano I, Filip T, Sauberer M, Caillé F, Breuil L, Stanek J, Freeman AF, Novarino G, Truillet C, Wanek T, Langer O. Tournier N, et al. Among authors: breuil l. J Cereb Blood Flow Metab. 2021 Jul;41(7):1634-1646. doi: 10.1177/0271678X20965500. Epub 2020 Oct 20. J Cereb Blood Flow Metab. 2021. PMID: 33081568 Free PMC article.

5

Imaging-Based Characterization of a Slco2b1^(-/-) Mouse Model Using [¹¹C]Erlotinib and [^99mTc]Mebrofenin as Probe Substrates.

Marie S, Hernández-Lozano I, Breuil L, Truillet C, Hu S, Sparreboom A, Tournier N, Langer O. Marie S, et al. Among authors: breuil l. Pharmaceutics. 2021 Jun 21;13(6):918. doi: 10.3390/pharmaceutics13060918. Pharmaceutics. 2021. PMID: 34205780 Free PMC article.

6

Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice?

Breuil L, Marie S, Goutal S, Auvity S, Truillet C, Saba W, Langer O, Caillé F, Tournier N. Breuil L, et al. J Cereb Blood Flow Metab. 2022 Jan;42(1):175-185. doi: 10.1177/0271678X211045444. Epub 2021 Sep 9. J Cereb Blood Flow Metab. 2022. PMID: 34496661 Free PMC article.

7

Radiolabeling and brain penetration of [¹¹ C]VU0071063, a ligand of type 1 sulfonylurea receptors for positron emission tomography imaging.

Caillé F, Saba W, Goutal S, Breuil L, Kuhnast B, Tournier N. Caillé F, et al. Among authors: breuil l. J Labelled Comp Radiopharm. 2022 Feb;65(2):28-35. doi: 10.1002/jlcr.3957. Epub 2021 Nov 30. J Labelled Comp Radiopharm. 2022. PMID: 34796549

8

[¹⁸F]2-Fluoro-2-deoxy-sorbitol PET Imaging for Quantitative Monitoring of Enhanced Blood-Brain Barrier Permeability Induced by Focused Ultrasound.

Hugon G, Goutal S, Dauba A, Breuil L, Larrat B, Winkeler A, Novell A, Tournier N. Hugon G, et al. Among authors: breuil l. Pharmaceutics. 2021 Oct 20;13(11):1752. doi: 10.3390/pharmaceutics13111752. Pharmaceutics. 2021. PMID: 34834167 Free PMC article.

9

Pharmacokinetic Imaging Using ^99mTc-Mebrofenin to Untangle the Pattern of Hepatocyte Transporter Disruptions Induced by Endotoxemia in Rats.

Marie S, Hernández-Lozano I, Le Vée M, Breuil L, Saba W, Goislard M, Goutal S, Truillet C, Langer O, Fardel O, Tournier N. Marie S, et al. Among authors: breuil l. Pharmaceuticals (Basel). 2022 Mar 24;15(4):392. doi: 10.3390/ph15040392. Pharmaceuticals (Basel). 2022. PMID: 35455390 Free PMC article.

10

Comparison of the Blood-Brain Barrier Transport and Vulnerability to P-Glycoprotein-Mediated Drug-Drug Interaction of Domperidone versus Metoclopramide Assessed Using In Vitro Assay and PET Imaging.

Breuil L, Goutal S, Marie S, Del Vecchio A, Audisio D, Soyer A, Goislard M, Saba W, Tournier N, Caillé F. Breuil L, et al. Pharmaceutics. 2022 Aug 9;14(8):1658. doi: 10.3390/pharmaceutics14081658. Pharmaceutics. 2022. PMID: 36015284 Free PMC article.

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