T-cell-derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2.
Yang J, Dang G, Lü S, Liu H, Ma X, Han L, Deng J, Miao Y, Li X, Shao F, Jiang C, Xu Q, Wang X, Feng J.
Yang J, et al. Among authors: dang g.
FASEB J. 2019 Nov;33(11):12780-12799. doi: 10.1096/fj.201900863R. Epub 2019 Aug 31.
FASEB J. 2019.
PMID: 31480861
Free PMC article.
Thus, PKM2-mediated EV ceramides in T cells may be an important cargo for T-cell-regulated B cell IgG production, and QD-CD19-PKM2-null T cell EVs hold high potential to treat B cell overactivation-related diseases.-Yang, J., Dang, G., Lu, S., Liu, H., Ma, X., Han, …
Thus, PKM2-mediated EV ceramides in T cells may be an important cargo for T-cell-regulated B cell IgG production, and QD-CD19-PKM2-null T ce …