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692 results

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High Polygenic Risk Is Associated with Earlier Initiation and Escalation of Treatment in Early Primary Open-Angle Glaucoma.
Marshall HN, Mullany S, Han X, Qassim A, He W, Hassall MM, Schmidt J, Thomson D, Nguyen TT, Berry EC, Knight LSW, Hollitt GL, Ridge B, Schulz A, Mills RA, Healey PR, Agar A, Galanopoulos A, Landers J, Graham SL, Hewitt AW, Casson RJ, MacGregor S, Siggs OM, Craig JE. Marshall HN, et al. Among authors: macgregor s. Ophthalmology. 2023 Aug;130(8):830-836. doi: 10.1016/j.ophtha.2023.03.028. Epub 2023 Apr 10. Ophthalmology. 2023. PMID: 37044160
Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals.
Hollitt GL, Siggs OM, Ridge B, Keane MC, Mackey DA, MacGregor S, Hewitt AW, Craig JE, Souzeau E. Hollitt GL, et al. Among authors: macgregor s. Transl Vis Sci Technol. 2022 Oct 3;11(10):38. doi: 10.1167/tvst.11.10.38. Transl Vis Sci Technol. 2022. PMID: 36306122 Free PMC article.
Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma.
Siggs OM, Qassim A, Han X, Marshall HN, Mullany S, He W, Souzeau E, Galanopoulos A, Agar A, Landers J, Casson RJ, Hewitt AW, Healey PR, Graham SL, MacGregor S, Craig JE. Siggs OM, et al. Among authors: macgregor s. JAMA Ophthalmol. 2022 Nov 10;141(1):73-7. doi: 10.1001/jamaophthalmol.2022.4688. Online ahead of print. JAMA Ophthalmol. 2022. PMID: 36355370 Free PMC article.
The Association of Alcohol Consumption with Glaucoma and Related Traits: Findings from the UK Biobank.
Stuart KV, Luben RN, Warwick AN, Madjedi KM, Patel PJ, Biradar MI, Sun Z, Chia MA, Pasquale LR, Wiggs JL, Kang JH, Kim J, Aschard H, Tran JH, Lentjes MAH, Foster PJ, Khawaja AP; Modifiable Risk Factors for Glaucoma Collaboration, the UK Biobank Eye and Vision Consortium, and the International Glaucoma Genetics Consortium; Members of the Modifiable Risk Factors for Glaucoma Collaboration; Members of the UK Biobank Eye and Vision Consortium; Members of the International Glaucoma Genetics Consortium. Stuart KV, et al. Ophthalmol Glaucoma. 2023 Jul-Aug;6(4):366-379. doi: 10.1016/j.ogla.2022.11.008. Epub 2022 Dec 5. Ophthalmol Glaucoma. 2023. PMID: 36481453 Free PMC article.
Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma.
Daniszewski M, Senabouth A, Liang HH, Han X, Lidgerwood GE, Hernández D, Sivakumaran P, Clarke JE, Lim SY, Lees JG, Rooney L, Gulluyan L, Souzeau E, Graham SL, Chan CL, Nguyen U, Farbehi N, Gnanasambandapillai V, McCloy RA, Clarke L, Kearns LS, Mackey DA, Craig JE, MacGregor S, Powell JE, Pébay A, Hewitt AW. Daniszewski M, et al. Among authors: macgregor s. Cell Genom. 2022 Jun 8;2(6):100142. doi: 10.1016/j.xgen.2022.100142. eCollection 2022 Jun 8. Cell Genom. 2022. PMID: 36778138 Free PMC article.
Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study.
Berry EC, Marshall HN, Mullany S, Torres SD, Schmidt J, Thomson D, Knight LSW, Hollitt GL, Qassim A, Ridge B, Schulz A, Hassall MM, Nguyen TT, Lake S, Mills RA, Agar A, Galanopoulos A, Landers J, Healey PR, Graham SL, Hewitt AW, MacGregor S, Casson RJ, Siggs OM, Craig JE. Berry EC, et al. Among authors: macgregor s. Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):11. doi: 10.1167/iovs.64.3.11. Invest Ophthalmol Vis Sci. 2023. PMID: 36867133 Free PMC article.
A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration.
Clark R, Lee SS, Du R, Wang Y, Kneepkens SCM, Charng J, Huang Y, Hunter ML, Jiang C, Tideman JWL, Melles RB, Klaver CCW, Mackey DA, Williams C, Choquet H, Ohno-Matsui K, Guggenheim JA; CREAM Consortium; UK Biobank Eye and Vision Consortium. Clark R, et al. EBioMedicine. 2023 May;91:104551. doi: 10.1016/j.ebiom.2023.104551. Epub 2023 Apr 11. EBioMedicine. 2023. PMID: 37055258 Free PMC article.
Genetic Risk Assessment of Degenerative Eye Disease (GRADE): study protocol of a prospective assessment of polygenic risk scores to predict diagnosis of glaucoma and age-related macular degeneration.
Hollitt GL, Qassim A, Thomson D, Schmidt JM, Nguyen TT, Landers J, MacGregor S, Siggs OM, Souzeau E, Craig JE. Hollitt GL, et al. Among authors: macgregor s. BMC Ophthalmol. 2023 Oct 24;23(1):431. doi: 10.1186/s12886-023-03143-5. BMC Ophthalmol. 2023. PMID: 37875865 Free PMC article.
692 results