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A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi.
Dos Reis TF, de Castro PA, Bastos RW, Pinzan CF, Souza PFN, Ackloo S, Hossain MA, Drewry DH, Alkhazraji S, Ibrahim AS, Jo H, Lightfoot JD, Adams EM, Fuller KK, deGrado WF, Goldman GH. Dos Reis TF, et al. Among authors: degrado wf. Nat Commun. 2023 Apr 12;14(1):2052. doi: 10.1038/s41467-023-37573-y. Nat Commun. 2023. PMID: 37045836 Free PMC article.
Patterning and folding of intestinal villi by active mesenchymal dewetting.
Huycke TR, Miyazaki H, Häkkinen TJ, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ. Huycke TR, et al. Among authors: degrado wf. bioRxiv [Preprint]. 2023 Aug 15:2023.06.25.546328. doi: 10.1101/2023.06.25.546328. bioRxiv. 2023. Update in: Cell. 2024 Jun 6;187(12):3072-3089.e20. doi: 10.1016/j.cell.2024.04.039 PMID: 37425793 Free PMC article. Updated. Preprint.
IL-13 and IL-17A Activate β1 Integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to Enhance Force Transmission in Airway Smooth Muscle.
Ngo U, Shi Y, Woodruff P, Shokat K, DeGrado W, Jo H, Sheppard D, Sundaram AB. Ngo U, et al. bioRxiv [Preprint]. 2024 May 1:2024.05.01.592042. doi: 10.1101/2024.05.01.592042. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e2401251121. doi: 10.1073/pnas.2401251121 PMID: 38746410 Free PMC article. Updated. Preprint.
Methods for high throughput discovery of fluoroprobes that recognize tau fibril polymorphs.
Carroll EC, Yang H, Jones JG, Oehler A, Charvat AF, Montgomery KM, Yung A, Millbern Z, Vinueza NR, DeGrado WF, Mordes DA, Condello C, Gestwicki JE. Carroll EC, et al. Among authors: degrado wf. bioRxiv [Preprint]. 2024 Sep 2:2024.09.02.610853. doi: 10.1101/2024.09.02.610853. bioRxiv. 2024. PMID: 39282355 Free PMC article. Preprint.
De novo design of peptides that bind specific conformers of α-synuclein.
Wallace HM, Yang H, Tan S, Pan HS, Yang R, Xu J, Jo H, Condello C, Polizzi NF, DeGrado WF. Wallace HM, et al. Among authors: degrado wf. Chem Sci. 2024 Mar 30;15(22):8414-8421. doi: 10.1039/d3sc06245g. eCollection 2024 Jun 5. Chem Sci. 2024. PMID: 38846390 Free PMC article.
Patterning and folding of intestinal villi by active mesenchymal dewetting.
Huycke TR, Häkkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ. Huycke TR, et al. Among authors: degrado wf. Cell. 2024 Jun 6;187(12):3072-3089.e20. doi: 10.1016/j.cell.2024.04.039. Epub 2024 May 22. Cell. 2024. PMID: 38781967 Free article.
453 results