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205 results

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Page 1
Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells.
Steiner I, Flores-Tellez TDNJ, Mevel R, Ali A, Wang P, Schofield P, Behan C, Forsythe N, Ashton G, Taylor C, Mills IG, Oliveira P, McDade SS, Zaiss DM, Choudhury A, Lacaud G, Baena E. Steiner I, et al. Among authors: ashton g. Cell Rep. 2023 Apr 25;42(4):112377. doi: 10.1016/j.celrep.2023.112377. Epub 2023 Apr 14. Cell Rep. 2023. PMID: 37060563 Free article.
Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer.
Barros-Silva JD, Linn DE, Steiner I, Guo G, Ali A, Pakula H, Ashton G, Peset I, Brown M, Clarke NW, Bronson RT, Yuan GC, Orkin SH, Li Z, Baena E. Barros-Silva JD, et al. Among authors: ashton g. Cell Rep. 2018 Dec 18;25(12):3504-3518.e6. doi: 10.1016/j.celrep.2018.11.069. Cell Rep. 2018. PMID: 30566873 Free PMC article.
TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.
Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V, Lacaud G, Murray GI, Sansom OJ, Hurlstone AFL, Malliri A. Diamantopoulou Z, et al. Among authors: ashton g. Cancer Cell. 2017 May 8;31(5):621-634.e6. doi: 10.1016/j.ccell.2017.03.007. Epub 2017 Apr 13. Cancer Cell. 2017. PMID: 28416184 Free PMC article.
Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non-small Cell Lung Cancer.
Salem A, Little RA, Latif A, Featherstone AK, Babur M, Peset I, Cheung S, Watson Y, Tessyman V, Mistry H, Ashton G, Behan C, Matthews JC, Asselin MC, Bristow RG, Jackson A, Parker GJM, Faivre-Finn C, Williams KJ, O'Connor JPB. Salem A, et al. Among authors: ashton g. Clin Cancer Res. 2019 Jul 1;25(13):3818-3829. doi: 10.1158/1078-0432.CCR-18-3932. Epub 2019 May 3. Clin Cancer Res. 2019. PMID: 31053599
Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma.
Girotti MR, Lopes F, Preece N, Niculescu-Duvaz D, Zambon A, Davies L, Whittaker S, Saturno G, Viros A, Pedersen M, Suijkerbuijk BM, Menard D, McLeary R, Johnson L, Fish L, Ejiama S, Sanchez-Laorden B, Hohloch J, Carragher N, Macleod K, Ashton G, Marusiak AA, Fusi A, Brognard J, Frame M, Lorigan P, Marais R, Springer C. Girotti MR, et al. Among authors: ashton g. Cancer Cell. 2015 Jan 12;27(1):85-96. doi: 10.1016/j.ccell.2014.11.006. Epub 2014 Dec 11. Cancer Cell. 2015. PMID: 25500121 Free PMC article.
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.
Lee RJ, Khandelwal G, Baenke F, Cannistraci A, Macleod K, Mundra P, Ashton G, Mandal A, Viros A, Gremel G, Galvani E, Smith M, Carragher N, Dhomen N, Miller C, Lorigan P, Marais R. Lee RJ, et al. Among authors: ashton g. ESMO Open. 2020 Aug;5(4):e000707. doi: 10.1136/esmoopen-2020-000707. ESMO Open. 2020. PMID: 32817058 Free PMC article.
Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin.
Torres-Ayuso P, Sahoo S, Ashton G, An E, Simms N, Galvin M, Leong HS, Frese KK, Simpson K, Cook N, Hughes A, Miller CJ, Marais R, Dive C, Krebs MG, Brognard J. Torres-Ayuso P, et al. Among authors: ashton g. NPJ Genom Med. 2018 Jun 20;3:15. doi: 10.1038/s41525-018-0055-6. eCollection 2018. NPJ Genom Med. 2018. PMID: 29951225 Free PMC article.
RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia.
Holland M, Castro FV, Alexander S, Smith D, Liu J, Walker M, Bitton D, Mulryan K, Ashton G, Blaylock M, Bagley S, Connolly Y, Bridgeman J, Miller C, Krishnan S, Dempsey C, Masurekar A, Stern P, Whetton A, Saha V. Holland M, et al. Among authors: ashton g. Blood. 2011 Jul 21;118(3):638-49. doi: 10.1182/blood-2010-09-307330. Epub 2011 May 23. Blood. 2011. PMID: 21606482 Free article.
205 results