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231 results

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Page 1
Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19.
Evering TH, Chew KW, Giganti MJ, Moser C, Pinilla M, Wohl DA, Currier JS, Eron JJ, Javan AC, Bender Ignacio R, Margolis D, Zhu Q, Ma J, Zhong L, Yan L, D'Andrea Nores U, Hoover K, Mocherla B, Choudhary MC, Deo R, Ritz J, Fischer WA, Fletcher CV, Li JZ, Hughes MD, Smith D, Daar ES; ACTIV-2/A5401 Study Team. Evering TH, et al. Among authors: fletcher cv. Ann Intern Med. 2023 May;176(5):658-666. doi: 10.7326/M22-3428. Epub 2023 Apr 18. Ann Intern Med. 2023. PMID: 37068272 Free PMC article. Clinical Trial.
Safety and efficacy of inhaled interferon-β1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trial.
Jagannathan P, Chew KW, Giganti MJ, Hughes MD, Moser C, Main MJ, Monk PD, Javan AC, Li JZ, Fletcher CV, McCarthy C, Wohl DA, Daar ES, Eron JJ, Currier JS, Singh U, Smith DM, Fischer W; ACTIV-2/A5401 Study Team. Jagannathan P, et al. Among authors: fletcher cv. EClinicalMedicine. 2023 Oct 6;65:102250. doi: 10.1016/j.eclinm.2023.102250. eCollection 2023 Nov. EClinicalMedicine. 2023. PMID: 37855026 Free PMC article.
Safety and Efficacy of SAB-185 for Nonhospitalized Adults With COVID-19: A Randomized Clinical Trial.
Chew KW, Taiwo BO, Moser C, Daar ES, Wohl DA, Ritz J, Javan AC, Li JZ, Fischer W, Greninger AL, Bausch C, Luke T, Call R, Neytman G, Giganti MJ, Fletcher CV, Hughes MD, Eron JJ, Currier JS, Smith DM; ACTIV-2/A5401 Study Team. Chew KW, et al. Among authors: fletcher cv. J Infect Dis. 2024 Nov 15;230(5):1177-1186. doi: 10.1093/infdis/jiae369. J Infect Dis. 2024. PMID: 39028902 Clinical Trial.
Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates.
Webb GM, Sauter KA, Takahashi D, Kirigiti M, Bader L, Lindsley SR, Blomenkamp H, Zaro C, Shallman M, McGuire C, Hofmeister H, Avila U, Pessoa C, Hwang JM, McCullen A, Humkey M, Reed J, Gao L, Winchester L, Fletcher CV, Varlamov O, Brown TT, Sacha JB, Kievit P, Roberts CT. Webb GM, et al. Among authors: fletcher cv. JCI Insight. 2024 Aug 8;9(18):e181968. doi: 10.1172/jci.insight.181968. JCI Insight. 2024. PMID: 39115937 Free PMC article.
Safety, Efficacy, and Pharmacokinetics of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies BMS-986414 (C135-LS) and BMS-986413 (C144-LS) Administered Subcutaneously in Non-Hospitalized Persons with COVID-19 in a Phase 2 Trial.
Corado KC, Chew KW, Giganti MJ, Mu Y, Fletcher CV, Currier JS, Daar ES, Wohl DA, Li JZ, Moser CB, Ritz J, Javan AC, Neytman G, Caskey M, Hughes MD, Smith DM, Eron JJ; ACTIV-2/A5401 Study Team. Corado KC, et al. Among authors: fletcher cv. Pathog Immun. 2024 May 6;9(1):138-155. doi: 10.20411/pai.v9i1.660. eCollection 2024. Pathog Immun. 2024. PMID: 38746756 Free PMC article.
In-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells.
Avedissian SN, Malik JR, Podany AT, Neely M, Rhodes NJ, Scarsi KK, Scheetz MH, Duryee MJ, Modebelu UO, Mykris TM, Winchester LC, Byrareddy SN, Fletcher CV. Avedissian SN, et al. Among authors: fletcher cv. Sci Rep. 2024 May 10;14(1):10709. doi: 10.1038/s41598-024-60935-5. Sci Rep. 2024. PMID: 38729980 Free PMC article.
Human bronchopulmonary disposition and plasma pharmacokinetics of oral bemnifosbuvir (AT-527), an experimental guanosine nucleotide prodrug for COVID-19.
Zhou XJ, Horga A, Puri A, Winchester L, Montrond M, Pietropaolo K, Belanger B, Fletcher CV, Hammond J. Zhou XJ, et al. Among authors: fletcher cv. J Antimicrob Chemother. 2024 Jun 3;79(6):1423-1431. doi: 10.1093/jac/dkae122. J Antimicrob Chemother. 2024. PMID: 38708557 Free PMC article. Clinical Trial.
Chemotherapy in pediatric brain tumor and the challenge of the blood-brain barrier.
Malik JR, Podany AT, Khan P, Shaffer CL, Siddiqui JA, Baranowska-Kortylewicz J, Le J, Fletcher CV, Ether SA, Avedissian SN. Malik JR, et al. Among authors: fletcher cv. Cancer Med. 2023 Dec;12(23):21075-21096. doi: 10.1002/cam4.6647. Epub 2023 Nov 23. Cancer Med. 2023. PMID: 37997517 Free PMC article. Review.
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection.
Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. Harwood OE, et al. Among authors: fletcher cv. PLoS Pathog. 2023 Sep 25;19(9):e1011676. doi: 10.1371/journal.ppat.1011676. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747933 Free PMC article.
231 results