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Page 1
Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome.
Cortez Cardoso Penha R, Smith-Byrne K, Atkins JR, Haycock PC, Kar S, Codd V, Samani NJ, Nelson C, Milojevic M, Gabriel AAG, Amos C, Brennan P, Hung RJ, Kachuri L, Mckay JD. Cortez Cardoso Penha R, et al. Among authors: samani nj. Elife. 2023 Apr 20;12:e83118. doi: 10.7554/eLife.83118. Elife. 2023. PMID: 37079368 Free PMC article.
Telomere length and brain imaging phenotypes in UK Biobank.
Topiwala A, Nichols TE, Williams LZJ, Robinson EC, Alfaro-Almagro F, Taschler B, Wang C, Nelson CP, Miller KL, Codd V, Samani NJ, Smith SM. Topiwala A, et al. Among authors: samani nj. PLoS One. 2023 Mar 22;18(3):e0282363. doi: 10.1371/journal.pone.0282363. eCollection 2023. PLoS One. 2023. PMID: 36947528 Free PMC article.
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls.
Preuss M, König IR, Thompson JR, Erdmann J, Absher D, Assimes TL, Blankenberg S, Boerwinkle E, Chen L, Cupples LA, Hall AS, Halperin E, Hengstenberg C, Holm H, Laaksonen R, Li M, März W, McPherson R, Musunuru K, Nelson CP, Burnett MS, Epstein SE, O'Donnell CJ, Quertermous T, Rader DJ, Roberts R, Schillert A, Stefansson K, Stewart AF, Thorleifsson G, Voight BF, Wells GA, Ziegler A, Kathiresan S, Reilly MP, Samani NJ, Schunkert H; CARDIoGRAM Consortium. Preuss M, et al. Among authors: samani nj. Circ Cardiovasc Genet. 2010 Oct;3(5):475-83. doi: 10.1161/CIRCGENETICS.109.899443. Epub 2010 Oct 5. Circ Cardiovasc Genet. 2010. PMID: 20923989 Free PMC article.
The transcriptional profile of iron deficiency in patients with heart failure: Heme-sparing and reduced immune processes.
Grote Beverborg N, Alnuwaysir RIS, Markousis-Mavrogenis G, Hoes MF, van der Wal HH, Romaine SPR, Nath M, Koekoemoer A, Cleland JGF, Lang CC, Anker SD, Dickstein K, Metra M, Ng LL, van Veldhuisen DJ, Voors AA, Samani NJ, van der Meer P. Grote Beverborg N, et al. Among authors: samani nj. Eur J Heart Fail. 2024 Dec 26. doi: 10.1002/ejhf.3562. Online ahead of print. Eur J Heart Fail. 2024. PMID: 39725571
Discovery of myosin light chain kinase gene variant in a patient with tetralogy of Fallot suffering aortic dissection: Implications for pathogenesis and the role of family and population screening.
Debiec R, Ebeid A, Hamby S, Anciunaite O, Illsley A, Nizam A, Iqbal M, Safwan K, Saifullah T, Bu'Lock F, Suzuki T, Samani NJ, Webb T, Bolger AP. Debiec R, et al. Among authors: samani nj. Int J Cardiol Congenit Heart Dis. 2024 Sep 18;18:100544. doi: 10.1016/j.ijcchd.2024.100544. eCollection 2024 Dec. Int J Cardiol Congenit Heart Dis. 2024. PMID: 39713234 Free PMC article.
Leucocyte telomere length and conduction system ageing.
van Duijvenboden S, Nelson CP, Raisi-Estabragh Z, Ramirez J, Orini M, Wang Q, Aung N, Codd V, Stoma S, Allara E, Wood AM, Di Angelantonio E, Danesh J, Harvey NC, Petersen SE, Munroe PB, Samani NJ. van Duijvenboden S, et al. Among authors: samani nj. Heart. 2024 Dec 17:heartjnl-2024-324875. doi: 10.1136/heartjnl-2024-324875. Online ahead of print. Heart. 2024. PMID: 39689933 Free article.
Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
Zheng SL, Henry A, Cannie D, Lee M, Miller D, McGurk KA, Bond I, Xu X, Issa H, Francis C, De Marvao A, Theotokis PI, Buchan RJ, Speed D, Abner E, Adams L, Aragam KG, Ärnlöv J, Raja AA, Backman JD, Baksi J, Barton PJR, Biddinger KJ, Boersma E, Brandimarto J, Brunak S, Bundgaard H, Carey DJ, Charron P, Cook JP, Cook SA, Denaxas S, Deleuze JF, Doney AS, Elliott P, Erikstrup C, Esko T, Farber-Eger EH, Finan C, Garnier S, Ghouse J, Giedraitis V, Guðbjartsson DF, Haggerty CM, Halliday BP, Helgadottir A, Hemingway H, Hillege HL, Kardys I, Lind L, Lindgren CM, Lowery BD, Manisty C, Margulies KB, Moon JC, Mordi IR, Morley MP, Morris AD, Morris AP, Morton L, Noursadeghi M, Ostrowski SR, Owens AT, Palmer CNA, Pantazis A, Pedersen OBV, Prasad SK, Shekhar A, Smelser DT, Srinivasan S, Stefansson K, Sveinbjörnsson G, Syrris P, Tammesoo ML, Tayal U, Teder-Laving M, Thorgeirsson G, Thorsteinsdottir U, Tragante V, Trégouët DA, Treibel TA, Ullum H, Valdes AM, van Setten J, van Vugt M, Veluchamy A, Verschuren WMM, Villard E, Yang Y; COVIDsortium; DBDS Genomic Consortium; Estonian Biobank Research Team; HERMES Consortium; Asselbergs FW, Cappola TP, Dube MP, Dunn ME, Ellinor PT, Hingorani AD, Lang CC, … See abstract for full author list ➔ Zheng SL, et al. Among authors: samani nj. Nat Genet. 2024 Dec;56(12):2646-2658. doi: 10.1038/s41588-024-01952-y. Epub 2024 Nov 21. Nat Genet. 2024. PMID: 39572783 Free PMC article.
Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease.
Trenkwalder T, Maj C, Al-Kassou B, Debiec R, Doppler SA, Musameh MD, Nelson CP, Dasmeh P, Grover S, Knoll K, Naamanka J, Mordi IR, Braund PS, Dreßen M, Lahm H, Wirth F, Baldus S, Kelm M, von Scheidt M, Krefting J, Ellinghaus D, Small AM, Peloso GM, Natarajan P, Thanassoulis G, Engert JC, Dufresne L, Franke A, Görg S, Laudes M, Nowak-Göttl U, Vaht M, Metspalu A, Stoll M, Berger K, Pellegrini C, Kastrati A, Hengstenberg C, Lang CC, Kessler T, Hovatta I, Nickenig G, Nöthen MM, Krane M, Schunkert H, Samani NJ, Schumacher J, Kals M, Reigo A, Teder-Laving M, Gehlen J, Webb TR, Giel AS, Koebbe LL, Feirer N, Billmann M, Srinivasan S, Zimmer S, Palmer CNA, Li L, Yang C, Borisov O, Adam M, Veulemans V, Joner M, Xhepa E; TARGET Consortium; Estonian Biobank; and the European Consortium for Genetics of Aortic Stenosis (EGAS). Trenkwalder T, et al. Among authors: samani nj. JAMA Cardiol. 2024 Nov 6:e243738. doi: 10.1001/jamacardio.2024.3738. Online ahead of print. JAMA Cardiol. 2024. PMID: 39504041
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